Elevated plasma cholesterol does not affect brain Abeta in mice lacking the low-density lipoprotein receptor. - Wikidata - awgldk - TriplyDB

Elevated plasma cholesterol does not affect brain Abeta in mice lacking the low-density lipoprotein receptor.

Elevated plasma cholesterol does not affect brain Abeta in mice lacking the low-density lipoprotein receptor.

http://www.wikidata.org/entity/Q48182034

about

Dysregulation of cholesterol balance in the brain: contribution to neurodegenerative diseases Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance Low-density lipoprotein receptor represents an apolipoprotein E-independent pathway of Aβ uptake and degradation by astrocytes Increased locomotor activity in mice lacking the low-density lipoprotein receptor Mouse models to study the effect of cardiovascular risk factors on brain structure and cognition The effects of cholesterol on learning and memory.Leptin reduces the accumulation of Abeta and phosphorylated tau induced by 27-hydroxycholesterol in rabbit organotypic slices Cholesterol and LDL relate to neuritic plaques and to APOE4 presence but not to neurofibrillary tangles Novel cerebrovascular pathology in mice fed a high cholesterol diet.IR and Raman imaging of murine brains from control and ApoE/LDLR(-/-) mice with advanced atherosclerosis.High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice.In situ mouse carotid perfusion model: glucose and cholesterol transport in the eye and brain.

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Elevated plasma cholesterol does not affect brain Abeta in mice lacking the low-density lipoprotein receptor.

http://www.wikidata.org/entity/Q48182034

description

2007 nî lūn-bûn

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年學術文章

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2007年學術文章

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2007年學術文章

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name

Elevated plasma cholesterol do ...... -density lipoprotein receptor.

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Elevated plasma cholesterol do ...... -density lipoprotein receptor.

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Elevated plasma cholesterol do ...... -density lipoprotein receptor.

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Elevated plasma cholesterol do ...... -density lipoprotein receptor.

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J.1471-4159.2007.04614.X

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Journal of Neurochemistry

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Elevated plasma cholesterol do ...... -density lipoprotein receptor.

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Gregory A Elder

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James Schmeidler

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Julie Y Cho

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Miguel A Gama Sosa

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Rita De Gasperi

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Sonia Franciosi

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Vahram Haroutunian

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P2860

Three-dimensional structure of the LDL receptor-binding domain of human apolipoprotein E

Convergence of atherosclerosis and Alzheimer's disease: inflammation, cholesterol, and misfolded proteins

ApoAI deficiency results in marked reductions in plasma cholesterol but no alterations in amyloid-beta pathology in a mouse model of Alzheimer's disease-like cerebral amyloidosis

The expression of native and oxidized LDL receptors in brain microvessels is specifically enhanced by astrocytes-derived soluble factor(s)

A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples

Localization of mRNA for low density lipoprotein receptor and a cholesterol synthetic enzyme in rabbit nervous system by in situ hybridization

Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation.

Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model.

Vascular risk factors for Alzheimer's disease: an epidemiologic perspective.

Dietary fat intake and the risk of incident dementia in the Rotterdam Study.

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1220-1231

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10.1111/J.1471-4159.2007.04614.X

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Joseph D. Buxbaum

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