MS565: A SPECT Tracer for Evaluating the Brain Penetration of BAF312 (Siponimod).

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Sphingosine 1-phosphate receptor 1 agonists: a patent review (2013-2015).Sphingosine 1-phosphate receptor modulation suppresses pathogenic astrocyte activation and chronic progressive CNS inflammation.Imaging Central Nervous System Demyelination and Remyelination by Positron-Emission Tomography.

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P2860

MS565: A SPECT Tracer for Evaluating the Brain Penetration of BAF312 (Siponimod).

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MS565: A SPECT Tracer for Evaluating the Brain Penetration of BAF312 (Siponimod).

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MS565: A SPECT Tracer for Evaluating the Brain Penetration of BAF312

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MS565: A SPECT Tracer for Evaluating the Brain Penetration of BAF312 (Siponimod).

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MS565: A SPECT Tracer for Evaluating the Brain Penetration of BAF312

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MS565: A SPECT Tracer for Evaluating the Brain Penetration of BAF312 (Siponimod).

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MS565: A SPECT Tracer for Evaluating the Brain Penetration of BAF312

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MS565: A SPECT Tracer for Evaluating the Brain Penetration of BAF312 (Siponimod).

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Emmanuelle Briard

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Joel A Krauser

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Sandrine Desrayaud

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P2860

Autoradiography, MALDI-MS, and SIMS-MS imaging in pharmaceutical discovery and development.

The selective sphingosine 1-phosphate receptor modulator BAF312 redirects lymphocyte distribution and has species-specific effects on heart rate.

Highly efficient route to fused polycyclic aromatics via palladium-catalyzed aryne annulation by aryl halides.

Discovery of BAF312 (Siponimod), a Potent and Selective S1P Receptor Modulator

Single-dose FTY720 pharmacokinetics, food effect, and pharmacological responses in healthy subjects.

Siponimod for patients with relapsing-remitting multiple sclerosis (BOLD): an adaptive, dose-ranging, randomised, phase 2 study.

A broadly applicable [18F]trifluoromethylation of aryl and heteroaryl iodides for PET imaging.

A universal procedure for the [¹⁸F]trifluoromethylation of aryl iodides and aryl boronic acids with highly improved specific activity.

Quantitative whole-body autoradiography in the pharmaceutical industry. Survey results on study design, methods, and regulatory compliance.

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1008-1018

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10.1002/CMDC.201500115

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2015-04-29T00:00:00Z

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25924727

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MS565: A SPECT Tracer for Evaluating the Brain Penetration of BAF312 (Siponimod).

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P2860

P2860

MS565: A SPECT Tracer for Evaluating the Brain Penetration of BAF312 (Siponimod).

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