(S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5.

(S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5.

Item
http://www.wikidata.org/entity/Q48205863
A Systematic Strategy for Discovering a Therapeutic Drug for Alzheimer's Disease and Its Target Molecule.(S)-lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation pharmacology.Reactive oxygen species induce neurite degeneration before induction of cell death.Efficacy of (S)-Lacosamide in preclinical models of cephalic pain.Hierarchical CRMP2 posttranslational modifications control NaV1.7 function.CRMPs Function in Neurons and Glial Cells: Potential Therapeutic Targets for Neurodegenerative Diseases and CNS Injury.Homology-guided mutational analysis reveals the functional requirements for antinociceptive specificity of collapsin response mediator protein 2-derived peptides.CRMP2 Phosphorylation Drives Glioblastoma Cell Proliferation.A single structurally conserved SUMOylation site in CRMP2 controls NaV1.7 function.Lacosamide inhibits calcitonin gene-related peptide production and release at trigeminal level in the rat.Loss of collapsin response mediator protein 4 suppresses dopaminergic neuron death in an 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease.CRMP2-Neurofibromin Interface Drives NF1-related Pain.CRMP2 and voltage-gated ion channels: potential roles in neuropathic pain
P2860

(S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5.

Item
http://www.wikidata.org/entity/Q48205863
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh-hant
name
(S)-Lacosamide Binding to Coll ...... g Its Phosphorylation by Cdk5.
@en
type
label
(S)-Lacosamide Binding to Coll ...... g Its Phosphorylation by Cdk5.
@en
prefLabel
(S)-Lacosamide Binding to Coll ...... g Its Phosphorylation by Cdk5.
@en
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P356
P1433
P1476
(S)-Lacosamide Binding to Coll ...... g Its Phosphorylation by Cdk5.
@en
P2093
P2860
P2888
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921