IGF-I-induced oligodendrocyte progenitor proliferation requires PI3K/Akt, MEK/ERK, and Src-like tyrosine kinases.
about
Insulin like growth factor-1-induced phosphorylation and altered distribution of tuberous sclerosis complex (TSC)1/TSC2 in C2C12 myotubesIGF-I: A Key Growth Factor that Regulates Neurogenesis and Synaptogenesis from Embryonic to Adult Stages of the BrainNeurodevelopmental effects of insulin-like growth factor signaling.IGF-1 promotes Brn-4 expression and neuronal differentiation of neural stem cells via the PI3K/Akt pathwayNeurotrophin-3 targets the translational initiation machinery in oligodendrocytes.The thrombin receptor is a critical extracellular switch controlling myelination.Constitutively active Akt induces enhanced myelination in the CNSRole of the Insulin-Like Growth Factor Type 1 Receptor in the Pathogenesis of Diabetic Encephalopathy.Erk1/2 MAPK and mTOR signaling sequentially regulates progression through distinct stages of oligodendrocyte differentiation.ERK1/ERK2 MAPK signaling is required to increase myelin thickness independent of oligodendrocyte differentiation and initiation of myelination.mTOR: a link from the extracellular milieu to transcriptional regulation of oligodendrocyte development.The antiaging protein Klotho enhances oligodendrocyte maturation and myelination of the CNS.Sustained activation of ERK1/2 MAPK in oligodendrocytes and schwann cells enhances myelin growth and stimulates oligodendrocyte progenitor expansion.Gastrointestinal growth factors and hormones have divergent effects on Akt activation.Adult-onset deficiency in growth hormone and insulin-like growth factor-I alters oligodendrocyte turnover in the corpus callosum.Intranasal administration of IGF-1 attenuates hypoxic-ischemic brain injury in neonatal rats.Leptin sustains spontaneous remyelination in the adult central nervous system.Experimental models for analysis of oligodendrocyte pathophysiology in stroke.Glia unglued: how signals from the extracellular matrix regulate the development of myelinating glia.Signaling mechanisms regulating myelination in the central nervous system.Extracellular cues influencing oligodendrocyte differentiation and (re)myelinationbeta-catenin mediates insulin-like growth factor-I actions to promote cyclin D1 mRNA expression, cell proliferation and survival in oligodendroglial culturesInsulin-like growth factor I regulates G2/M progression through mammalian target of rapamycin signaling in oligodendrocyte progenitors.TAPP1 inhibits the differentiation of oligodendrocyte precursor cells via suppressing the Mek/Erk pathwayAstrocytes protect oligodendrocyte precursor cells via MEK/ERK and PI3K/Akt signaling.Interference with Protease-activated Receptor 1 Alleviates Neuronal Cell Death Induced by Lipopolysaccharide-Stimulated Microglial Cells through the PI3K/Akt Pathway.New metformin derivative HL156A prevents oral cancer progression by inhibiting the insulin-like growth factor/AKT/mammalian target of rapamycin pathways.Hypoxic Preconditioning Augments the Therapeutic Efficacy of Bone Marrow Stromal Cells in a Rat Ischemic Stroke Model.High-mobility group box-1 as an autocrine trophic factor in white matter stroke.MiR-1260b inhibitor enhances the chemosensitivity of colorectal cancer cells to fluorouracil by targeting PDCD4/IGF1Galectin-3-Mediated Glial Crosstalk Drives Oligodendrocyte Differentiation and (Re)myelination
P2860
Q24307579-E00EFFF6-29E7-4E08-A484-1971D8624032Q26768613-862844F0-19B4-4F01-91A4-0928ECE3F55EQ30451424-2FD57FE8-FC52-443B-8E5D-E7451EB9EFF9Q34634074-1185D949-99CB-420B-9EC3-DD16EEC18004Q34992053-EBE0C23B-64EE-4D2D-AAB9-94A6E26A3607Q35217740-DD36A6C8-9EE0-487C-BA49-2D4EAA21A177Q35394901-CC908688-8770-480D-89D2-191CCB4E7725Q35672446-D021D601-AC91-4E54-B6B2-456A41D78FE3Q35693398-64ACF777-998F-41A7-B95C-BF192B6278FFQ36464562-E68DD356-DA0F-46AC-A3A3-E4A516731EB0Q36697506-EE0E2EFD-EF64-4034-9D72-EE9AAE08317AQ37012784-A229D739-C7F9-48F3-89E9-22A2BB6AB850Q37014142-0AF2BA57-6CA6-46C6-BCE4-489F9D2CAEB2Q37180159-42736540-D760-4622-BFF1-58F32B6D6016Q37228020-10172A31-28A0-4A47-861D-E29D3D5F39AFQ37397977-69AC2671-8C14-4114-B3CF-AD66C8DA8224Q37587696-EBFCFA5A-3D67-4B68-A317-1DBC730D3F52Q37691262-108BC2BF-96FD-47EC-90CF-08A26DD1A104Q37915435-3CBC222F-1196-422B-A571-9D7516F943C8Q38096247-DDAD79F9-EE57-4742-BA29-A2FBB5A29F07Q38789322-429CB065-9722-4B60-BEE6-28ACBE274C9AQ39726709-C3D47769-234E-4E6F-8FDD-C28C50C09E0FQ41035104-28611528-DFDB-4197-9DA1-B66E1CF0C1F4Q41465204-21A591CA-9DFE-4A89-BFA4-5940982E03DFQ41835555-BE7FF6B6-E731-40D8-B86D-8937611C0290Q42359958-C54DFE0A-1C06-4455-BCD6-55F00870F2B5Q47246957-484EB28D-7826-493D-9073-C3B9BDEF5136Q48218622-6710AA92-BA68-4C93-88A7-A8D008BD2A22Q48325544-E7BAF4EF-EC34-462F-B98A-9230C72FA449Q57144441-0A38744B-A138-4817-9292-C6C8921344DDQ57157917-DDDD46E5-4F06-48F0-A1E5-B9D8161E1BF8
P2860
IGF-I-induced oligodendrocyte progenitor proliferation requires PI3K/Akt, MEK/ERK, and Src-like tyrosine kinases.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
IGF-I-induced oligodendrocyte ...... and Src-like tyrosine kinases.
@en
IGF-I-induced oligodendrocyte ...... and Src-like tyrosine kinases.
@nl
type
label
IGF-I-induced oligodendrocyte ...... and Src-like tyrosine kinases.
@en
IGF-I-induced oligodendrocyte ...... and Src-like tyrosine kinases.
@nl
prefLabel
IGF-I-induced oligodendrocyte ...... and Src-like tyrosine kinases.
@en
IGF-I-induced oligodendrocyte ...... and Src-like tyrosine kinases.
@nl
P2860
P1476
IGF-I-induced oligodendrocyte ...... and Src-like tyrosine kinases.
@en
P2093
Guillermina Almazan
Qiao-Ling Cui
P2860
P304
P356
10.1111/J.1471-4159.2006.04329.X
P407
P577
2007-03-01T00:00:00Z