Melanoma mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia. - Wikidata - awgldk - TriplyDB

Melanoma mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia.

Melanoma mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia.

http://www.wikidata.org/entity/Q48250298

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Oncogenic mutations in GNAQ occur early in uveal melanoma Protease-Activated Receptors and other G-Protein-Coupled Receptors: the Melanoma Connection Exosomes: The Link between GPCR Activation and Metastatic Potential?Current State of Animal (Mouse) Modeling in Melanoma Research Melanoma: from mutations to medicine Effects of G-protein mutations on skin color Impaired gp100-Specific CD8(+) T-Cell Responses in the Presence of Myeloid-Derived Suppressor Cells in a Spontaneous Mouse Melanoma Model I-SceI-mediated double-strand break does not increase the frequency of homologous recombination at the Dct locus in mouse embryonic stem cells Metabotropic glutamate receptors: from the workbench to the bedside.Metabotropic glutamate receptors (mGlus) and cellular transformation.Serum glutamate levels correlate with Gleason score and glutamate blockade decreases proliferation, migration, and invasion and induces apoptosis in prostate cancer cells Rare-earth-doped biological composites as in vivo shortwave infrared reporters Metabotropic glutamate receptor 1 (Grm1) is an oncogene in epithelial cells.Activation of the glutamate receptor GRM1 enhances angiogenic signaling to drive melanoma progression.Metabotropic glutamate receptors as a new therapeutic target for malignant gliomas Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer.AKT2 is a downstream target of metabotropic glutamate receptor 1 (Grm1).A phase 0 trial of riluzole in patients with resectable stage III and IV melanoma Tumor-reactive CD4(+) T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts Metabotropic glutamate receptor 1 mediates melanocyte transformation via transactivation of insulin-like growth factor 1 receptor.Oncogenic activities of metabotropic glutamate receptor 1 (Grm1) in melanocyte transformation Glutamate and its receptors in cancer Systematic analysis of somatic mutations in phosphorylation signaling predicts novel cancer drivers Non-canonical Smads phosphorylation induced by the glutamate release inhibitor, riluzole, through GSK3 activation in melanoma Riluzole mediates anti-tumor properties in breast cancer cells independent of metabotropic glutamate receptor-1.Location-dependent signaling of the group 1 metabotropic glutamate receptor mGlu5.Chemical-genetic screen identifies riluzole as an enhancer of Wnt/β-catenin signaling in melanoma Hypoxia-inducible factors enhance glutamate signaling in cancer cells A new transgenic mouse line for tetracycline inducible transgene expression in mature melanocytes and the melanocyte stem cells using the Dopachrome tautomerase promoter.Genetic analysis of the GRM1 gene in human melanoma susceptibility.Metabotropic glutamate receptor 1 expression and its polymorphic variants associate with breast cancer phenotypes.Melanoma brain colonization involves the emergence of a brain-adaptive phenotype Lentivector prime and vaccinia virus vector boost generate high-quality CD8 memory T cells and prevent autochthonous mouse melanoma.Exome sequencing identifies GRIN2A as frequently mutated in melanoma.Identification of novel GRM1 mutations and single nucleotide polymorphisms in prostate cancer cell lines and tissues.Expression of the metabotropic glutamate receptor 5 (mGluR5) induces melanoma in transgenic mice.Glutamate secretion and metabotropic glutamate receptor 1 expression during Kaposi's sarcoma-associated herpesvirus infection promotes cell proliferation.A Genome Wide Study of Copy Number Variation Associated with Nasopharyngeal Carcinoma in Malaysian Chinese Identifies CNVs at 11q14.3 and 6p21.3 as Candidate Loci.Delving into somatic variation in sporadic melanoma.Exon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma.

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P2860

Melanoma mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia.

http://www.wikidata.org/entity/Q48250298

description

2003 nî lūn-bûn

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Melanoma mouse model implicate ...... ling in melanocytic neoplasia.

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Melanoma mouse model implicate ...... ling in melanocytic neoplasia.

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Melanoma mouse model implicate ...... ling in melanocytic neoplasia.

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Melanoma mouse model implicate ...... ling in melanocytic neoplasia.

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Melanoma mouse model implicate ...... ling in melanocytic neoplasia.

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Amy Chen

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Arturo Incao

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Aruna Koganti

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10.1038/NG1148

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