Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type.
about
The amyloid-beta precursor protein: integrating structure with biological functionLocalization of a susceptibility gene for common forms of stroke to 5q12Protein aggregation in the brain: the molecular basis for Alzheimer's and Parkinson's diseasesStabilization of neurotoxic soluble beta-sheet-rich conformations of the Alzheimer's disease amyloid-beta peptideBACE2, a beta -secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor proteinCerebral amyloid angiopathy: amyloid beta accumulates in putative interstitial fluid drainage pathways in Alzheimer's diseaseIntracerebral haemorrhage in Down syndrome: protected or predisposed?Tau Protein Hyperphosphorylation and Aggregation in Alzheimer's Disease and Other Tauopathies, and Possible Neuroprotective StrategiesA Unified Hypothesis of Early- and Late-Onset Alzheimer's Disease PathogenesisMitochondrial abnormalities in Alzheimer's disease: possible targets for therapeutic interventionGenetic heterogeneity in Alzheimer disease and implications for treatment strategiesAlzheimer's disease pathologic cascades: who comes first, what drives whatAlzheimer's pathogenesis and its link to the mitochondrionInconsistencies and controversies surrounding the amyloid hypothesis of Alzheimer's diseaseNeural stem cells could serve as a therapeutic material for age-related neurodegenerative diseasesA knowledge network for a dynamic taxonomy of psychiatric diseaseThe genetics of Alzheimer diseaseCrystal Structure of the E2 Domain of Amyloid Precursor Protein-like Protein 1 in Complex with Sucrose OctasulfateRab GTPases, membrane trafficking and diseasesDo Microglia Default on Network Maintenance in Alzheimer's Disease?Three dimensions of the amyloid hypothesis: time, space and 'wingmen'Analyzing dendritic spine pathology in Alzheimer's disease: problems and opportunitiesDense-core senile plaques in the Flemish variant of Alzheimer's disease are vasocentricMedin-amyloid: a recently characterized age-associated arterial amyloid form affects mainly arteries in the upper part of the bodyTrafficking and proteolytic processing of APPIn vitro studies of amyloid beta-protein fibril assembly and toxicity provide clues to the aetiology of Flemish variant (Ala692-->Gly) Alzheimer's diseaseAbeta amyloid fibrils possess a core structure highly resistant to hydrogen exchangeIntroduction of hereditary disease-associated mutations into the beta-amyloid precursor protein gene of mouse embryonic stem cells: a comparison of homologous recombination methodsNonhuman primate models of Alzheimer-like cerebral proteopathyThe Japanese Mutant Aβ (ΔE22-Aβ1−39) Forms Fibrils Instantaneously, with Low-Thioflavin T Fluorescence: Seeding of Wild-Type Aβ1−40into Atypical Fibrils by ΔE22-Aβ1−39Familial Alzheimer's disease Osaka mutant (ΔE22) β-barrels suggest an explanation for the different Aβ1-40/42 preferred conformational states observed by experiment.The DNA laboratory and neurological practice.Early accumulation of intracellular fibrillar oligomers and late congophilic amyloid angiopathy in mice expressing the Osaka intra-Aβ APP mutation.Structural heterogeneity in familial Alzheimer's disease mutants of amyloid-beta peptides.Alzheimer's disease: pathophysiology and applications of magnetic nanoparticles as MRI theranostic agents.The amyloid cascade-inflammatory hypothesis of Alzheimer disease: implications for therapy.Amyloid beta protein (Abeta) starts to deposit as plasma membrane-bound form in diffuse plaques of brains from hereditary cerebral hemorrhage with amyloidosis-Dutch type, Alzheimer disease and nondemented aged subjects.Differential degradation of amyloid beta genetic variants associated with hereditary dementia or stroke by insulin-degrading enzyme.Structure and dynamics of the Abeta(21-30) peptide from the interplay of NMR experiments and molecular simulations.Codeposition of cystatin C with amyloid-beta protein in the brain of Alzheimer disease patients.
P2860
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P2860
Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type.
description
1990 nî lūn-bûn
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1990年の論文
@ja
1990年学术文章
@wuu
1990年学术文章
@zh
1990年学术文章
@zh-cn
1990年学术文章
@zh-hans
1990年学术文章
@zh-my
1990年学术文章
@zh-sg
1990年學術文章
@yue
1990年學術文章
@zh-hant
name
Mutation of the Alzheimer's di ...... rebral hemorrhage, Dutch type.
@en
Mutation of the Alzheimer's di ...... rebral hemorrhage, Dutch type.
@nl
type
label
Mutation of the Alzheimer's di ...... rebral hemorrhage, Dutch type.
@en
Mutation of the Alzheimer's di ...... rebral hemorrhage, Dutch type.
@nl
prefLabel
Mutation of the Alzheimer's di ...... rebral hemorrhage, Dutch type.
@en
Mutation of the Alzheimer's di ...... rebral hemorrhage, Dutch type.
@nl
P2093
P356
P1433
P1476
Mutation of the Alzheimer's di ...... rebral hemorrhage, Dutch type.
@en
P2093
Fernandez-Madrid IJ
Frangione B
Lieberburg I
Luyendijk W
van Duinen SG
P304
P356
10.1126/SCIENCE.2111584
P407
P577
1990-06-01T00:00:00Z