High-throughput retroviral tagging to identify components of specific signaling pathways in cancer.
about
Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitorGenome-wide interrogation of Mammalian stem cell fate determinants by nested chromosome deletionsNF-kappaB1 p105 negatively regulates TPL-2 MEK kinase activityStructural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1Mice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factorsPIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancersInsertional mutagenesis reveals progression genes and checkpoints in MYC/Runx2 lymphomasDomain-wide regulation of gene expression in the human genomeRetroviruses 2004: review of the 2004 Cold Spring Harbor Retroviruses ConferenceMatrix attachment regions as targets for retroviral integrationSIP1/ZEB2 induces EMT by repressing genes of different epithelial cell-cell junctionsMouse models for the discovery of colorectal cancer driver genesThe utility of transposon mutagenesis for cancer studies in the era of genome editing.From cytopenia to leukemia: the role of Gfi1 and Gfi1b in blood formationTargeting the Pim kinases in multiple myelomaMYC activation is a hallmark of cancer initiation and maintenanceDetecting statistically significant common insertion sites in retroviral insertional mutagenesis screensThe oncogenic role of the ETS transcription factors MEF and ERGInsights into the nuclear export of murine leukemia virus intron-containing RNAA small-molecule inhibitor of PIM kinases as a potential treatment for urothelial carcinomasHematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integrationActivation of alternative Jdp2 promoters and functional protein isoforms in T-cell lymphomas by retroviral insertion mutagenesisThe RUNX genes: gain or loss of function in cancerThe PIM kinases in hematological cancersFgf10 is an oncogene activated by MMTV insertional mutagenesis in mouse mammary tumors and overexpressed in a subset of human breast carcinomasActivation of an oncogenic microRNA cistron by provirus integrationRegulation and function of TPL-2, an IκB kinase-regulated MAP kinase kinase kinaseThe serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitorThe common viral insertion site Evi12 is located in the 5'-noncoding region of Gnn, a novel gene with enhanced expression in two subclasses of human acute myeloid leukemiaPim1 serine/threonine kinase regulates the number and functions of murine hematopoietic stem cellsGenetic screens using the piggyBac transposonA DNA transposon-based approach to validate oncogenic mutations in the mouseA recessive genetic screen for host factors required for retroviral infection in a library of insertionally mutated Blm-deficient embryonic stem cells.MicroRNAs and genomic instability.Pim-1 kinase phosphorylates RUNX family transcription factors and enhances their activityReal-time definition of non-randomness in the distribution of genomic eventsOrthologous microRNA genes are located in cancer-associated genomic regions in human and mousePvt1-encoded microRNAs in oncogenesis.Identification of novel Bach2 transcripts and protein isoforms through tagging analysis of retroviral integrations in B-cell lymphomas.A piggyBac transposon-based genome-wide library of insertionally mutated Blm-deficient murine ES cells.
P2860
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P2860
High-throughput retroviral tagging to identify components of specific signaling pathways in cancer.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
High-throughput retroviral tag ...... signaling pathways in cancer.
@en
High-throughput retroviral tag ...... signaling pathways in cancer.
@nl
type
label
High-throughput retroviral tag ...... signaling pathways in cancer.
@en
High-throughput retroviral tag ...... signaling pathways in cancer.
@nl
prefLabel
High-throughput retroviral tag ...... signaling pathways in cancer.
@en
High-throughput retroviral tag ...... signaling pathways in cancer.
@nl
P2093
P356
P1433
P1476
High-throughput retroviral tag ...... signaling pathways in cancer.
@en
P2093
Anton Berns
Augustinus Hart
Edwin Vink
Harald Mikkers
John Allen
Like Romeijn
Puck Knipscheer
P2888
P304
P356
10.1038/NG950
P407
P577
2002-08-19T00:00:00Z