cDNA cloning and sequencing of a new gene intensely expressed in early differentiation stages of embryonal carcinoma cells and in mid-gestation period of mouse embryogenesis.
about
Solution structure of midkine, a new heparin-binding growth factorSerum midkine levels are increased in patients with various types of carcinomasCorrelation of elevated level of blood midkine with poor prognostic factors of human neuroblastomasMidkine and cytoplasmic maturation of mammalian oocytes in the context of ovarian follicle physiologyStructure and function of midkine as the basis of its pharmacological effectsInvolvement of midkine in neuroblastoma tumourigenesisRegulation of Pleiotrophin, Midkine, Receptor Protein Tyrosine Phosphatase β/ζ, and Their Intracellular Signaling Cascades in the Nucleus Accumbens During Opiate AdministrationStructural requirements of heparan sulfate for the binding to the tumor-derived adhesion factor/angiomodulin that induces cord-like structures to ECV-304 human carcinoma cellsCloning, characterization and developmental regulation of two members of a novel human gene family of neurite outgrowth-promoting proteinsMidkine induces tumor cell proliferation and binds to a high affinity signaling receptor associated with JAK tyrosine kinasesNeurite outgrowth in brain neurons induced by heparin-binding growth-associated molecule (HB-GAM) depends on the specific interaction of HB-GAM with heparan sulfate at the cell surfaceHuman ryudocan from endothelium-like cells binds basic fibroblast growth factor, midkine, and tissue factor pathway inhibitorInvolvement of receptor-like protein tyrosine phosphatase zeta/RPTPbeta and its ligand pleiotrophin/heparin-binding growth-associated molecule (HB-GAM) in neuronal migrationHaptotactic migration induced by midkine. Involvement of protein-tyrosine phosphatase zeta. Mitogen-activated protein kinase, and phosphatidylinositol 3-kinase6B4 proteoglycan/phosphacan, an extracellular variant of receptor-like protein-tyrosine phosphatase zeta/RPTPbeta, binds pleiotrophin/heparin-binding growth-associated molecule (HB-GAM)Pleiotrophin/heparin-binding growth-associated molecule as a mitogen of rat hepatocytes and its role in regeneration and development of liverNeointima formation in a restenosis model is suppressed in midkine-deficient miceRegulation and localization of midkine in rat ovaryMidkine, heparin-binding growth factor, blocks kainic acid-induced seizure and neuronal cell death in mouse hippocampusA Receptor-like Protein-tyrosine Phosphatase PTP /RPTP Binds a Heparin-binding Growth Factor Midkine: INVOLVEMENT OF ARGININE 78 OF MIDKINE IN THE HIGH AFFINITY BINDING TO PTPInvolvement of heparin affin regulatory peptide in human prostate cancer.Pleiotrophin induces angiogenesis: involvement of the phosphoinositide-3 kinase but not the nitric oxide synthase pathways.Identification of candidate angiogenic inhibitors processed by matrix metalloproteinase 2 (MMP-2) in cell-based proteomic screens: disruption of vascular endothelial growth factor (VEGF)/heparin affin regulatory peptide (pleiotrophin) and VEGF/ConneMidkine is a NF-kappaB-inducible gene that supports prostate cancer cell survival.Expression of midkine and its clinical significance in esophageal squamous cell carcinoma.Diagnostic accuracy of ELISA for detecting serum Midkine in cancer patients.Effects of human midkine on spontaneous resorption of herniated intervertebral discs.The role of pleiotrophin and beta-catenin in fetal lung development.Enhanced therapeutic effects of combined chemotherapeutic drugs and midkine antisense oligonucleotides for hepatocellular carcinomaBone turnover in wild type and pleiotrophin-transgenic mice housed for three months in the International Space Station (ISS)Nuclear targeting by the growth factor midkine.Pleiotrophin (PTN) expression and function and in the mouse mammary gland and mammary epithelial cells.The Drosophila midkine/pleiotrophin homologues Miple1 and Miple2 affect adult lifespan but are dispensable for alk signaling during embryonic gut formation.Premature ligand-receptor interaction during biosynthesis limits the production of growth factor midkine and its receptor LDL receptor-related protein 1Growth factor midkine is involved in the pathogenesis of diabetic nephropathy.Midkine, a potential link between obesity and insulin resistanceStimulation of the midkine/ALK axis renders glioma cells resistant to cannabinoid antitumoral actionMidkine is expressed and differentially processed during chronic obstructive pulmonary disease exacerbations and ventilator-associated pneumonia associated with Staphylococcus aureus infection.Midkine: a promising molecule for drug development to treat diseases of the central nervous systemEukaryotic Expression and Purification of Native Form of Mouse Midkine from Pichia pastoris.
P2860
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P2860
cDNA cloning and sequencing of a new gene intensely expressed in early differentiation stages of embryonal carcinoma cells and in mid-gestation period of mouse embryogenesis.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年学术文章
@wuu
1988年学术文章
@zh-cn
1988年学术文章
@zh-hans
1988年学术文章
@zh-my
1988年学术文章
@zh-sg
1988年學術文章
@yue
1988年學術文章
@zh
1988年學術文章
@zh-hant
name
cDNA cloning and sequencing of ...... period of mouse embryogenesis.
@en
cDNA cloning and sequencing of ...... period of mouse embryogenesis.
@nl
type
label
cDNA cloning and sequencing of ...... period of mouse embryogenesis.
@en
cDNA cloning and sequencing of ...... period of mouse embryogenesis.
@nl
prefLabel
cDNA cloning and sequencing of ...... period of mouse embryogenesis.
@en
cDNA cloning and sequencing of ...... period of mouse embryogenesis.
@nl
P2093
P1476
cDNA cloning and sequencing of ...... period of mouse embryogenesis.
@en
P2093
Kadomatsu K
Muramatsu T
Tomomura M
P304
P356
10.1016/S0006-291X(88)80505-9
P407
P577
1988-03-01T00:00:00Z