Design and synthesis of a MAO-B-selectively activated prodrug based on MPTP: a mitochondria-targeting chemotherapeutic agent for treatment of human malignant gliomas.
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Successful Treatment of Intracranial Glioblastoma Xenografts With a Monoamine Oxidase B-Activated Pro-Drug.Monoamine oxidase B levels are highly expressed in human gliomas and are correlated with the expression of HiF-1α and with transcription factors Sp1 and Sp3.Intracranial Glioblastomas: New Hope for an Effective Treatment.A perspective on multi-target drug discovery and design for complex diseases.PAM-OBG: A monoamine oxidase B specific prodrug that inhibits MGMT and generates DNA interstrand crosslinks, potentiating temozolomide and chemoradiation therapy in intracranial glioblastoma.Proanthocyanidins exert a neuroprotective effect via ROS/JNK signaling in MPTP‑induced Parkinson's disease models in vitro and in vivo
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Design and synthesis of a MAO-B-selectively activated prodrug based on MPTP: a mitochondria-targeting chemotherapeutic agent for treatment of human malignant gliomas.
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2015 nî lūn-bûn
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2015年の論文
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name
Design and synthesis of a MAO- ...... nt of human malignant gliomas.
@en
Design and synthesis of a MAO- ...... nt of human malignant gliomas.
@nl
type
label
Design and synthesis of a MAO- ...... nt of human malignant gliomas.
@en
Design and synthesis of a MAO- ...... nt of human malignant gliomas.
@nl
prefLabel
Design and synthesis of a MAO- ...... nt of human malignant gliomas.
@en
Design and synthesis of a MAO- ...... nt of human malignant gliomas.
@nl
P2093
P2860
P356
P1433
P1476
Design and synthesis of a MAO- ...... nt of human malignant gliomas.
@en
P2093
Alexandra M Baskin
David S Baskin
Junyan Han
Martyn A Sharpe
P2860
P304
P356
10.1002/CMDC.201402562
P577
2015-02-11T00:00:00Z