Matrix metalloprotease 8-dependent extracellular matrix cleavage at the blood-CSF barrier contributes to lethality during systemic inflammatory diseases.
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The choroid plexus-cerebrospinal fluid interface in Alzheimer's disease: more than just a barrierFriends or Foes: Matrix Metalloproteinases and Their Multifaceted Roles in Neurodegenerative DiseasesPathogens penetrating the central nervous system: infection pathways and the cellular and molecular mechanisms of invasionEndotoxemia-mediated inflammation potentiates aminoglycoside-induced ototoxicity.Endothelial LRP1 transports amyloid-β(1-42) across the blood-brain barrierEndothelial Response to Glucocorticoids in Inflammatory DiseasesMatrix metalloproteinases in inflammatory bowel disease: an updateMechanisms of long-term cognitive dysfunction of sepsis: from blood-borne leukocytes to glial cellsLRP1 Modulates APP Intraneuronal Transport and Processing in Its Monomeric and Dimeric StateConcerted regulation of retinal pigment epithelium basement membrane and barrier function by angiocrine factors.Soluble biglycan as a biomarker of inflammatory renal diseases.Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studiesBlood-Brain Barrier Deterioration and Hippocampal Gene Expression in Polymicrobial Sepsis: An Evaluation of Endothelial MyD88 and the Vagus NerveSynthesis and Validation of a Hydroxypyrone-Based, Potent, and Specific Matrix Metalloproteinase-12 Inhibitor with Anti-Inflammatory Activity In Vitro and In Vivo.The pediatric sepsis biomarker risk model: potential implications for sepsis therapy and biology.Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF.Identification of a novel mechanism of blood-brain communication during peripheral inflammation via choroid plexus-derived extracellular vesicles.MMP-3 Deficiency Alleviates Endotoxin-Induced Acute Inflammation in the Posterior Eye Segment.Microbial Translocation Associated with an Acute-Phase Response and Elevations in MMP-1, HO-1, and Proinflammatory Cytokines in Strongyloides stercoralis Infection.Suppression of gelatinase activity in human peripheral blood mononuclear cells by verapamil.A new angle on blood-CNS interfaces: a role for connexins?Matrix Metalloproteinase-8 is a Novel Pathogenetic Factor in Focal Cerebral Ischemia.Psychiatric disturbances regulate the innate immune system in CSF of conscious mice.Directional Fluid Transport across Organ-Blood Barriers: Physiology and Cell Biology.Brain Barrier Breakdown as a Cause and Consequence of Neuroinflammation in Sepsis.Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice.Systemic matrix metalloproteinase-8 and tissue inhibitor of metalloproteinases-1 levels in severe sepsis-associated coagulopathy.Association of MMP-8 with obesity, smoking and insulin resistance.Development and Validation of a Small Single-domain Antibody That Effectively Inhibits Matrix Metalloproteinase 8.TNFR1 inhibition with a Nanobody protects against EAE development in mice.Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017.Dual targeting of cancer-related human matrix metalloproteinases and carbonic anhydrases by chiral N-(biarylsulfonyl)-phosphonic acids.A Hidden Epithelial Barrier in the Brain with a Central Role in Regulating Brain Homeostasis. Implications for Aging.Pro-inflammatory effects of matrix metalloproteinase 7 in acute inflammation.Local Radiotherapy Affects Drug Pharmacokinetics-Exploration of a Neglected but Significant Uncertainty of Cancer Therapy.Matrix Metalloproteinase-8 Inhibition Prevents Disruption of Blood-Spinal Cord Barrier and Attenuates Inflammation in Rat Model of Spinal Cord Injury.Matrix metalloproteinase-14 triggers an anti-inflammatory proteolytic cascade in endotoxemia.Counteracting the effects of TNF receptor-1 has therapeutic potential in Alzheimer's disease.A New Venue of TNF Targeting.Serum Markers of Blood-Brain Barrier Remodeling and Fibrosis as Predictors of Etiology and Clinicoradiologic Outcome in Intracerebral Hemorrhage
P2860
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P2860
Matrix metalloprotease 8-dependent extracellular matrix cleavage at the blood-CSF barrier contributes to lethality during systemic inflammatory diseases.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh-hant
name
Matrix metalloprotease 8-depen ...... ystemic inflammatory diseases.
@en
Matrix metalloprotease 8-depen ...... ystemic inflammatory diseases.
@nl
type
label
Matrix metalloprotease 8-depen ...... ystemic inflammatory diseases.
@en
Matrix metalloprotease 8-depen ...... ystemic inflammatory diseases.
@nl
prefLabel
Matrix metalloprotease 8-depen ...... ystemic inflammatory diseases.
@en
Matrix metalloprotease 8-depen ...... ystemic inflammatory diseases.
@nl
P2093
P50
P1476
Matrix metalloprotease 8-depen ...... ystemic inflammatory diseases.
@en
P2093
Claude Libert
Conor Mc Guire
Delphine Demeestere
Elien Van Wonterghem
Eline Dejonckheere
Filip Van Hauwermeiren
Georges Leclercq
Ineke Vanlaere
Leen Puimège
Philippe Van Lint
P304
P356
10.1523/JNEUROSCI.0967-12.2012
P407
P577
2012-07-01T00:00:00Z