The 5-lipoxygenase enzymatic pathway in the mouse brain: young versus old.
about
The 5-lipoxygenase pathway: oxidative and inflammatory contributions to the Alzheimer's disease phenotypeStructural and functional rejuvenation of the aged brain by an approved anti-asthmatic drug.Cysteinyl Leukotrienes and Their Receptors: Emerging Therapeutic Targets in Central Nervous System DisordersInvolvement of 5-lipoxygenase in the corticosteroid-dependent amyloid beta formation: in vitro and in vivo evidenceGene knockout of 5-lipoxygenase rescues synaptic dysfunction and improves memory in the triple-transgenic model of Alzheimer's disease.5-Lipoxygenase DNA methylation and mRNA content in the brain and heart of young and old mice.FLAP pharmacological blockade modulates metabolism of endogenous tau in vivo .5-Lipoxygenase in mouse cerebellar Purkinje cellsLeukotriene B4, administered via intracerebroventricular injection, attenuates the antigen-induced asthmatic response in sensitized guinea pigsKnockout of 5-lipoxygenase results in age-dependent anxiety-like behavior in female mice.Zileuton restores memory impairments and reverses amyloid and tau pathology in aged Alzheimer's disease miceEffects of minocycline on cocaine sensitization and phosphorylation of GluR1 receptors in 5-lipoxygenase deficient miceCyclooxygenases and 5-lipoxygenase in Alzheimer's disease.5-lipoxygenase as an endogenous modulator of amyloid β formation in vivo.Pharmacologic blockade of 5-lipoxygenase improves the amyloidotic phenotype of an Alzheimer's disease transgenic mouse model involvement of γ-secretaseZileuton improves memory deficits, amyloid and tau pathology in a mouse model of Alzheimer's disease with plaques and tangles.Adeno-associated virus-mediated brain delivery of 5-lipoxygenase modulates the AD-like phenotype of APP mice.Pharmacologic inhibition of 5-lipoxygenase improves memory, rescues synaptic dysfunction, and ameliorates tau pathology in a transgenic model of tauopathy.Effect of aging on 5-hydroxymethylcytosine in the mouse hippocampus.Involvement of 5-lipoxygenase activating protein in the amyloidotic phenotype of an Alzheimer's disease mouse model5-Lipoxygenase gene transfer worsens memory, amyloid, and tau brain pathologies in a mouse model of Alzheimer disease.The involvement of 5-lipoxygenase activating protein in anxiety-like behaviorIncreased 5-lipoxygenase immunoreactivity in the hippocampus of patients with Alzheimer's disease.The influence of 5-lipoxygenase on Alzheimer's disease-related tau pathology: in vivo and in vitro evidence.5-Lipoxygenase gene disruption reduces amyloid-beta pathology in a mouse model of Alzheimer's diseaseA Novel Inhibitor of 5-Lipoxygenase (5-LOX) Prevents Oxidative Stress-Induced Cell Death of Retinal Pigment Epithelium (RPE) Cells5-Lipoxygenase in the Prefrontal Cortex of Suicide Victims.Modulation of multiple pathways involved in the maintenance of neuronal function during aging by fisetin.5-Lipoxygenase and epigenetic DNA methylation in aging cultures of cerebellar granule cellsModulation of lipopolysaccharide-induced memory insult, γ-secretase, and neuroinflammation in triple transgenic mice by 5-lipoxygenase.Homocysteine modulates 5-lipoxygenase expression level via DNA methylation.Novel lipid signaling pathways in Alzheimer's disease pathogenesis.Molecular biomarkers of lung carcinoma.The Lipoxygenases: Their Regulation and Implication in Alzheimer's Disease.The 5-Lipoxygenase as modulator of Alzheimer's γ-secretase and therapeutic target.Effects of MK-886, a 5-lipoxygenase activating protein (FLAP) inhibitor, and 5-lipoxygenase deficiency on the forced swimming behavior of miceInhibition of leukotriene receptors boosts neural progenitor proliferation.Low-dose oral sirolimus reduces atherogenesis, vascular inflammation and modulates plaque composition in mice lacking the LDL receptorPossible role for interactions between 5-lipoxygenase (5-LOX) and AMPA GluR1 receptors in depression and in antidepressant therapy.The 5-lipoxygenase as a common pathway for pathological brain and vascular aging
P2860
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P2860
The 5-lipoxygenase enzymatic pathway in the mouse brain: young versus old.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
The 5-lipoxygenase enzymatic pathway in the mouse brain: young versus old.
@en
The 5-lipoxygenase enzymatic pathway in the mouse brain: young versus old.
@nl
type
label
The 5-lipoxygenase enzymatic pathway in the mouse brain: young versus old.
@en
The 5-lipoxygenase enzymatic pathway in the mouse brain: young versus old.
@nl
prefLabel
The 5-lipoxygenase enzymatic pathway in the mouse brain: young versus old.
@en
The 5-lipoxygenase enzymatic pathway in the mouse brain: young versus old.
@nl
P2093
P1476
The 5-lipoxygenase enzymatic pathway in the mouse brain: young versus old.
@en
P2093
Cinzia M Chinnici
Domenico Praticò
Yuemang Yao
P304
P356
10.1016/J.NEUROBIOLAGING.2006.06.007
P577
2006-08-22T00:00:00Z