Thyroid hormone receptor DNA binding is required for both positive and negative gene regulation. - Wikidata - awgldk - TriplyDB

Thyroid hormone receptor DNA binding is required for both positive and negative gene regulation.

Thyroid hormone receptor DNA binding is required for both positive and negative gene regulation.

http://www.wikidata.org/entity/Q48452249

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Regulation of regional expression in rat brain PC2 by thyroid hormone/characterization of novel negative thyroid hormone response elements in the PC2 promoter Rapid signaling at the plasma membrane by a nuclear receptor for thyroid hormone An intact DNA-binding domain is not required for peroxisome proliferator-activated receptor gamma (PPARgamma) binding and activation on some PPAR response elements.Complete activation of thyroid hormone receptor β by T3 is essential for normal cochlear function and morphology in mice.Thyroid hormone action in the absence of thyroid hormone receptor DNA-binding in vivo Thyroid hormone exerts negative feedback on hypothalamic type 4 melanocortin receptor expression.Differential regulation of steroidogenic enzyme genes by TRα signaling in testicular Leydig cells.The thyrotropin-releasing hormone gene is regulated by thyroid hormone at the level of transcription in vivo.Dissecting the Relation between a nuclear receptor and GATA: binding affinity studies of thyroid hormone receptor and GATA2 on TSHβ promoter.E1A and a nuclear receptor corepressor splice variant (N-CoRI) are thyroid hormone receptor coactivators that bind in the corepressor mode.Negative regulation by thyroid hormone receptor requires an intact coactivator-binding surface.3, 3'5 Triiodo L thyronine induces apoptosis in human breast cancer MCF-7 cells, repressing SMP30 expression through negative thyroid response elements.The interaction between nuclear receptor corepressor and histone deacetylase 3 regulates both positive and negative thyroid hormone action in vivo.Liver X receptor regulation of thyrotropin-releasing hormone transcription in mouse hypothalamus is dependent on thyroid status Mechanisms of thyroid hormone action Crosstalk between thyroid hormone receptor and liver X receptor in the regulation of selective Alzheimer's disease indicator-1 gene expression.Thyroid hormone and COUP-TF1 regulate kallikrein-binding protein (KBP) gene expression.Krüppel-like factors are effectors of nuclear receptor signaling.Thyroid hormone action: a binding contract Selective activators of thyroid hormone receptors.Fundamentally distinct roles of thyroid hormone receptor isoforms in a thyrotroph cell line are due to differential DNA binding.Thyroid hormone receptors and resistance to thyroid hormone disorders.Minireview: The neural regulation of the hypothalamic-pituitary-thyroid axis.Molecular characterization of thyroid hormone receptor beta from Schistosoma japonicum and assessment of its potential as a vaccine candidate antigen against schistosomiasis in BALB/c mice General background on the hypothalamic-pituitary-thyroid (HPT) axis.Current and potential rodent screens and tests for thyroid toxicants.Molecular physiology of pituitary development: signaling and transcriptional networks.Nuclear corepressors mediate the repression of phospholipase A2 group IIa gene transcription by thyroid hormone A thyroid hormone receptor mutation that dissociates thyroid hormone regulation of gene expression in vivo.In vivo interaction of steroid receptor coactivator (SRC)-1 and the activation function-2 domain of the thyroid hormone receptor (TR) beta in TRbeta E457A knock-in and SRC-1 knockout mice.Negative regulation by nuclear receptors: a plethora of mechanisms.New insights on thyroid hormone mediated regulation of herpesvirus infections.The N-CoR/histone deacetylase 3 complex is required for repression by thyroid hormone receptor.Potential Role of Thyroid Receptor β Agonists in the Treatment of Hyperlipidemia.Binding of the thyroid hormone receptor to a negative element in the basal growth hormone promoter is associated with histone acetylation.To bind or not to bind - how to down-regulate target genes by liganded thyroid hormone receptor?Site-specific basicities regulate molecular recognition in receptor binding: in silico docking of thyroid hormones.Noncanonical thyroid hormone signaling mediates cardiometabolic effects in vivo.Naturally Occurring Amino Acids in Helix 10 of the Thyroid Hormone Receptor Mediate Isoform-Specific TH Gene Regulation.Reversing thyroid-hormone-mediated repression of a HSV-1 promoter via computationally guided mutagenesis.

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Thyroid hormone receptor DNA binding is required for both positive and negative gene regulation.

http://www.wikidata.org/entity/Q48452249

description

2002 nî lūn-bûn

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2002年の論文

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年學術文章

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2002年學術文章

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Thyroid hormone receptor DNA b ...... and negative gene regulation.

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Thyroid hormone receptor DNA b ...... and negative gene regulation.

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type

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Thyroid hormone receptor DNA b ...... and negative gene regulation.

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Thyroid hormone receptor DNA b ...... and negative gene regulation.

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Thyroid hormone receptor DNA b ...... and negative gene regulation.

@en

Thyroid hormone receptor DNA b ...... and negative gene regulation.

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Journal of Biological Chemistry

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Thyroid hormone receptor DNA b ...... and negative gene regulation.

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P2093

Anthony N Hollenberg

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Fredric E Wondisford

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Nobuyuki Shibusawa

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P2860

The c-erb-A gene encodes a thyroid hormone receptor

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

Isolation and characterization of a novel ligand-dependent thyroid hormone receptor-coactivating protein

Nuclear receptor corepressors activate rather than suppress basal transcription of genes that are negatively regulated by thyroid hormone

Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA

Structural determinants of nuclear receptor assembly on DNA direct repeats

The steroid and thyroid hormone receptor superfamily

Divergent roles for thyroid hormone receptor beta isoforms in the endocrine axis and auditory system.

Rb interacts with histone deacetylase to repress transcription

The c-erb-A protein is a high-affinity receptor for thyroid hormone

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732-738

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scholarly article

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10.1074/JBC.M207264200

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2

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278

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2002-11-04T00:00:00Z

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12419821

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