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DNAJC13 mutations in Parkinson diseasePalmitoylation of δ-catenin by DHHC5 mediates activity-induced synapse plasticityLeptin: a novel therapeutic target in Alzheimer's disease?Chronic and acute LRRK2 silencing has no long-term behavioral effects, whereas wild-type and mutant LRRK2 overexpression induce motor and cognitive deficits and altered regulation of dopamine release.Synaptic function is modulated by LRRK2 and glutamate release is increased in cortical neurons of G2019S LRRK2 knock-in mice.Initial elevations in glutamate and dopamine neurotransmission decline with age, as does exploratory behavior, in LRRK2 G2019S knock-in miceLRRK2 overexpression alters glutamatergic presynaptic plasticity, striatal dopamine tone, postsynaptic signal transduction, motor activity and memory.Robotic multiwell planar patch-clamp for native and primary mammalian cells.Behavioral deficits and striatal DA signaling in LRRK2 p.G2019S transgenic rats: a multimodal investigation including PET neuroimaging.Retromer-dependent neurotransmitter receptor trafficking to synapses is altered by the Parkinson's disease VPS35 mutation p.D620N.Atypical progressive supranuclear palsy with corticospinal tract degeneration.The pathological and physical effects of AB protein on the subunits of voltage gated potassium channels : From cell lines to human diseaseCav2.3 channels contribute to dopaminergic neuron loss in a model of Parkinson's diseaseApplication of CRISPR/Cas9 editing and digital droplet PCR in human iPSCs to generate novel knock-in reporter lines to visualize dopaminergic neurons
P50
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P50
description
hulumtues
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onderzoeker
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հետազոտող
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Dayne A Beccano-Kelly
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Dayne A Beccano-Kelly
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Dayne A Beccano-Kelly
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Dayne A Beccano-Kelly
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Dayne Aaron Beccano-Kely
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Dayne Aaron Beccano-Kely
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Dayne Aaron Beccano-Kely
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Dayne Aaron Beccano-Kely
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type
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Dayne A Beccano-Kelly
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Dayne A Beccano-Kelly
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Dayne A Beccano-Kelly
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Dayne A Beccano-Kelly
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Dayne Aaron Beccano-Kely
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Dayne Aaron Beccano-Kely
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Dayne Aaron Beccano-Kely
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Dayne Aaron Beccano-Kely
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Dayne Aaron Beccano-Kely
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Dayne Aaron Beccano-Kely
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altLabel
Dayne Aaron Beccano-Kely
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Dayne Aaron Beccano-Kely
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Dayne Aaron Beccano-Kely
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Dayne Aaron Beccano-Kely
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Dayne Beccano-Kelly
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prefLabel
Dayne A Beccano-Kelly
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Dayne A Beccano-Kelly
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Dayne A Beccano-Kelly
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Dayne A Beccano-Kelly
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Dayne Aaron Beccano-Kely
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Dayne Aaron Beccano-Kely
@de
Dayne Aaron Beccano-Kely
@en-ca
Dayne Aaron Beccano-Kely
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Dayne Aaron Beccano-Kely
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Dayne Aaron Beccano-Kely
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P108
P106
P21
P213
0000 0004 2697 2596
P31
P496
0000-0003-3592-8354
P569
2000-01-01T00:00:00Z