Effect of a new inhibitor of the synthesis of 20-HETE on cerebral ischemia reperfusion injury.
about
Cyclooxygenase- and cytochrome P450-derived eicosanoids in strokeAssociation of common variants of CYP4A11 and CYP4F2 with stroke in the Han Chinese populationSoluble Epoxide Hydrolase Inhibition: Targeting Multiple Mechanisms of Ischemic Brain Injury with a Single AgentEffect of 20-HETE inhibition on infarct volume and cerebral blood flow after transient middle cerebral artery occlusion.Cytochrome P450 metabolites of arachidonic acid play a role in the enhanced cardiac dysfunction in diabetic rats following ischaemic reperfusion injury.Association of 1347 G/A cytochrome P450 4F2 (CYP4F2) gene variant with hypertension and stroke.The inhibitor of 20-HETE synthesis, TS-011, improves cerebral microcirculatory autoregulation impaired by middle cerebral artery occlusion in mice.Cerebrospinal fluid 20-HETE is associated with delayed cerebral ischemia and poor outcomes after aneurysmal subarachnoid hemorrhage.Impaired myogenic response and autoregulation of cerebral blood flow is rescued in CYP4A1 transgenic Dahl salt-sensitive rat.Cytochrome 4A11 Genetic Polymorphisms Increase Susceptibility to Ischemic Stroke and Associate with Atherothrombotic Events After Stroke in ChineseAttenuation of neonatal ischemic brain damage using a 20-HETE synthesis inhibitorProtective effect of 20-HETE inhibition in a model of oxygen-glucose deprivation in hippocampal slice cultures.Additive Neuroprotection of a 20-HETE Inhibitor with Delayed Therapeutic Hypothermia after Hypoxia-Ischemia in Neonatal PigletsCerebral Perfusion Enhancing Interventions: A New Strategy for the Prevention of Alzheimer Dementia.Identification of a region of rat chromosome 1 that impairs the myogenic response and autoregulation of cerebral blood flow in fawn-hooded hypertensive rats.Interaction Between CYP4F2 rs2108622 and CPY4A11 rs9333025 Variants Is Significantly Correlated with Susceptibility to Ischemic Stroke and 20-Hydroxyeicosatetraenoic Acid Level.Human cytochrome p450 family 4 enzymes: function, genetic variation and regulation.Elevated production of 20-HETE in the cerebral vasculature contributes to severity of ischemic stroke and oxidative stress in spontaneously hypertensive rats.20-HETE-mediated cytotoxicity and apoptosis in ischemic kidney epithelial cells.Intravenous formulation of N-hydroxy-N'-(4-n-butyl-2-methylphenyl)formamidine (HET0016) for inhibition of rat brain 20-hydroxyeicosatetraenoic acid formationEndothelin rather than 20-HETE contributes to loss of pial arteriolar dilation during focal cerebral ischemia with and without polymeric hemoglobin transfusionMolecular mechanisms and cell signaling of 20-hydroxyeicosatetraenoic acid in vascular pathophysiology.Emerging role of G protein-coupled receptors in microvascular myogenic tone.Clinical Implications of 20-Hydroxyeicosatetraenoic Acid in the Kidney, Liver, Lung and Brain: An Emerging Therapeutic Target20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertensionEicosanoids and their drugs in cardiovascular diseases: focus on atherosclerosis and stroke.Role of cytochrome P450-mediated arachidonic acid metabolites in the pathogenesis of cardiac hypertrophy.P450 Eicosanoids and Reactive Oxygen Species Interplay in Brain Injury and Neuroprotection.Cytochrome P450 eicosanoids in cerebrovascular function and disease.Expression of CYP 4A ω-hydroxylase and formation of 20-hydroxyeicosatetreanoic acid (20-HETE) in cultured rat brain astrocytes.Increase of 20-HETE synthase after brain ischemia in rats revealed by PET study with 11C-labeled 20-HETE synthase-specific inhibitor.20-Hydroxyeicosatetraenoic Acid Inhibition by HET0016 Offers Neuroprotection, Decreases Edema, and Increases Cortical Cerebral Blood Flow in a Pediatric Asphyxial Cardiac Arrest Model in Rats.Cerebrovascular reactivity in acute hyperoxia in patients with acute ischaemic stroke.Thrombotic stroke in the anesthetized monkey (Macaca mulatta): characterization by MRI--a pilot study.Upregulation of 20-HETE Synthetic Cytochrome P450 Isoforms by Oxygen-Glucose Deprivation in Cortical Neurons.
P2860
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P2860
Effect of a new inhibitor of the synthesis of 20-HETE on cerebral ischemia reperfusion injury.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Effect of a new inhibitor of t ...... l ischemia reperfusion injury.
@en
Effect of a new inhibitor of t ...... l ischemia reperfusion injury.
@nl
type
label
Effect of a new inhibitor of t ...... l ischemia reperfusion injury.
@en
Effect of a new inhibitor of t ...... l ischemia reperfusion injury.
@nl
prefLabel
Effect of a new inhibitor of t ...... l ischemia reperfusion injury.
@en
Effect of a new inhibitor of t ...... l ischemia reperfusion injury.
@nl
P2093
P1433
P1476
Effect of a new inhibitor of t ...... l ischemia reperfusion injury.
@en
P2093
Chie Koizumi
David R Harder
Kenji Hachiuma
Misako Fukasawa
Noriyuki Miyata
Richard J Roman
Shigeru Okuyama
Shigeru Yoshida
Shiro Nakaike
Takanobu Sakurai
P304
P356
10.1161/01.STR.0000217398.37075.07
P407
P577
2006-04-06T00:00:00Z