about
Novel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli CellsMaternal age-dependent APC/C-mediated decrease in securin causes premature sister chromatid separation in meiosis II.Cell cycle-dependent regulation of structure of endoplasmic reticulum and inositol 1,4,5-trisphosphate-induced Ca2+ release in mouse oocytes and embryos.Ca2+ signalling and cortical re-organisation during the transition from meiosis to mitosis in mammalian oocytes.A spindle assembly checkpoint protein functions in prophase I arrest and prometaphase progressionA cell cycle-associated change in Ca2+ releasing activity leads to the generation of Ca2+ transients in mouse embryos during the first mitotic divisionConventional PKCs regulate the temporal pattern of Ca2+ oscillations at fertilization in mouse eggs.DNA damage-induced metaphase I arrest is mediated by the spindle assembly checkpoint and maternal age.Cytoplasmic Determination of Meiotic Spindle Size Revealed by a Unique Inter-Species Germinal Vesicle Transfer ModelThe DNA damage response in mammalian oocytes.Identification of an activation site in Bak and mitochondrial Bax triggered by antibodies.Mitochondrial function and redox state in mammalian embryos.Dual-mode regulation of the APC/C by CDK1 and MAPK controls meiosis I progression and fidelity.The role of calcium in mammalian oocyte maturation and egg activation.Development of oocyte banks and systems for the in-vitro development of oocytes: future directions for the treatment of infertility.Label-free in vivo Raman microspectroscopic imaging of the macromolecular architecture of oocytes.Ca2+ release and the development of Ca2+ release mechanisms during oocyte maturation: a prelude to fertilization.Follicle-stimulating hormone induces a gap junction-dependent dynamic change in [cAMP] and protein kinase a in mammalian oocytes.The ability to develop an activity that transfers histones onto sperm chromatin is acquired with meiotic competence during oocyte growth.The dynamics of plasma membrane PtdIns(4,5)P(2) at fertilization of mouse eggs.Securin regulates entry into M-phase by modulating the stability of cyclin B.Developmentally acquired PKA localisation in mouse oocytes and embryos.Cell cycle-dependent Ca2+ oscillations in mouse embryos are regulated by nuclear targeting of PLCzeta.Sperm-triggered [Ca2+] oscillations and Ca2+ homeostasis in the mouse egg have an absolute requirement for mitochondrial ATP production.The dynamics of cyclin B1 distribution during meiosis I in mouse oocytes.Cyclin A2 modulates kinetochore-microtubule attachment in meiosis II.Regulation of cytosolic and mitochondrial ATP levels in mouse eggs and zygotes.Mitochondrial dysfunction in oocytes of obese mothers: transmission to offspring and reversal by pharmacological endoplasmic reticulum stress inhibitors.Measurement of ATP in single oocytes: impact of maturation and cumulus cells on levels and consumption.Oocytes progress beyond prophase in the presence of DNA damage.Changes in endoplasmic reticulum structure during mouse oocyte maturation are controlled by the cytoskeleton and cytoplasmic dynein.Ca2+ oscillations at fertilization in mammals are regulated by the formation of pronuclei.The ability to generate normal Ca(2+) transients in response to spermatozoa develops during the final stages of oocyte growth and maturation.Epigenetic modifications during oocyte growth correlates with extended parthenogenetic development in the mouse.Nuclei from fertilized mouse embryos have calcium-releasing activity.Spatiotemporal dynamics of intracellular [Ca2+]i oscillations during the growth and meiotic maturation of mouse oocytes.Rac activity is polarized and regulates meiotic spindle stability and anchoring in mammalian oocytes.Regulation of redox metabolism in the mouse oocyte and embryo.Expression of inositol 1,4,5-trisphosphate receptors in mouse oocytes and early embryos: the type I isoform is upregulated in oocytes and downregulated after fertilization.Effect of gonadotrophin environment on growth and development of isolated mouse primary ovarian follicles.
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description
hulumtues
@sq
onderzoeker
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researcher
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հետազոտող
@hy
name
John Carroll
@ast
John Carroll
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John Carroll
@es
John Carroll
@nl
John Carroll
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type
label
John Carroll
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John Carroll
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John Carroll
@es
John Carroll
@nl
John Carroll
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prefLabel
John Carroll
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John Carroll
@en
John Carroll
@es
John Carroll
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John Carroll
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P106
P21
P31
P496
0000-0001-9644-5861