Role of human nucleoside transporters in the uptake and cytotoxicity of azacitidine and decitabine.

Role of human nucleoside transporters in the uptake and cytotoxicity of azacitidine and decitabine.

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http://www.wikidata.org/entity/Q48655141
How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusionPredicting response to epigenetic therapyStructural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transportersHuman concentrative nucleoside transporter 3 transfection with ultrasound and microbubbles in nucleoside transport deficient HEK293 cells greatly increases gemcitabine uptake.Nucleoside transporters and human organic cation transporter 1 determine the cellular handling of DNA-methyltransferase inhibitors.Nucleoside transporter proteins as biomarkers of drug responsiveness and drug targets.Decitabine inhibits the cell growth of cholangiocarcinoma in cultured cell lines and mouse xenografts.Acquired resistance to decitabine and cross-resistance to gemcitabine during the long-term treatment of human HCT116 colorectal cancer cells with decitabine.Digging deep into "dirty" drugs - modulation of the methylation machinery.Efficacy of decitabine-loaded nanogels in overcoming cancer drug resistance is mediated via sustained DNA methyltransferase 1 (DNMT1) depletion.High expression of the human equilibrative nucleoside transporter 1 gene predicts a good response to decitabine in patients with myelodysplastic syndrome.DNA methyltransferase inhibitors in cancer: a chemical and therapeutic patent overview and selected clinical studies.Decitabine nanoconjugate sensitizes human glioblastoma cells to temozolomideEpigenetic regulation of melanoma tumor suppressor miRNA-124a.
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Role of human nucleoside transporters in the uptake and cytotoxicity of azacitidine and decitabine.

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http://www.wikidata.org/entity/Q48655141
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh-hant
name
Role of human nucleoside trans ...... of azacitidine and decitabine.
@en
Role of human nucleoside trans ...... of azacitidine and decitabine.
@nl
type
label
Role of human nucleoside trans ...... of azacitidine and decitabine.
@en
Role of human nucleoside trans ...... of azacitidine and decitabine.
@nl
prefLabel
Role of human nucleoside trans ...... of azacitidine and decitabine.
@en
Role of human nucleoside trans ...... of azacitidine and decitabine.
@nl
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Role of human nucleoside trans ...... of azacitidine and decitabine.
@en
P2093
P2860
P304
P31
P356
10.1080/15257770.2011.652330
P433
P478
P577
P698
P921