Kainate receptors coexist in a functional complex with KCC2 and regulate chloride homeostasis in hippocampal neurons.
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KCC2 regulates actin dynamics in dendritic spines via interaction with β-PIX.Molecular and evolutionary insights into the structural organization of cation chloride cotransportersNeuronal Chloride Regulation via KCC2 Is Modulated through a GABAB Receptor Protein Complex.Cation-chloride cotransporters in neuronal development, plasticity and diseaseKCC2 activity is critical in limiting the onset and severity of status epilepticus.Selective inhibition of KCC2 leads to hyperexcitability and epileptiform discharges in hippocampal slices and in vivoNeto2-null mice have impaired GABAergic inhibition and are susceptible to seizures.Kinase-KCC2 coupling: Cl- rheostasis, disease susceptibility, therapeutic target.Regulation of neuronal chloride homeostasis by neuromodulators.Neto2 Assembles with Kainate Receptors in DRG Neurons during Development and Modulates Neurite Outgrowth in Adult Sensory Neurons.Genetic predisposition and early life experience interact to determine glutamate transporter (GLT1) and solute carrier family 12 member 5 (KCC2) levels in rat hippocampus.The membrane trafficking and functionality of the K+-Cl- co-transporter KCC2 is regulated by TGF-β2.Compromised GABAergic inhibition contributes to tumor-associated epilepsy.Native KCC2 interactome reveals PACSIN1 as a critical regulator of synaptic inhibitionGABAA receptor dependent synaptic inhibition rapidly tunes KCC2 activity via the Cl--sensitive WNK1 kinase.Molecular architecture of potassium chloride co-transporter KCC2.K+-Cl- co-transporter 2 (KCC2) - a membrane trafficking perspective.Emerging Mechanisms Underlying Dynamics of GABAergic Synapses.Restoring GABAergic inhibition rescues memory deficits in a Huntington's disease mouse model.A kainate receptor subunit promotes the recycling of the neuron-specific K+-Cl- co-transporter KCC2 in hippocampal neurons.
P2860
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P2860
Kainate receptors coexist in a functional complex with KCC2 and regulate chloride homeostasis in hippocampal neurons.
description
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name
Kainate receptors coexist in a ...... stasis in hippocampal neurons.
@en
Kainate receptors coexist in a ...... stasis in hippocampal neurons.
@nl
type
label
Kainate receptors coexist in a ...... stasis in hippocampal neurons.
@en
Kainate receptors coexist in a ...... stasis in hippocampal neurons.
@nl
prefLabel
Kainate receptors coexist in a ...... stasis in hippocampal neurons.
@en
Kainate receptors coexist in a ...... stasis in hippocampal neurons.
@nl
P2093
P50
P1433
P1476
Kainate receptors coexist in a ...... ostasis in hippocampal neurons
@en
P2093
Andrew Puchalski
Brooke A Acton
Caiwei M Li
Eric Delpire
Evgueni A Ivakine
Jessica C Pressey
Jonah Chevrier
Michelle Y Huang
Roderick R McInnes
P304
P356
10.1016/J.CELREP.2014.05.022
P577
2014-06-05T00:00:00Z