Memory deficits correlating with acetylcholinesterase splice shift and amyloid burden in doubly transgenic mice.
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Interactions of AChE with Aβ Aggregates in Alzheimer's Brain: Therapeutic Relevance of IDN 5706Behavioral assays with mouse models of Alzheimer's disease: practical considerations and guidelines.Heterologous amyloid seeding: revisiting the role of acetylcholinesterase in Alzheimer's disease.Structural elements regulating amyloidogenesis: a cholinesterase model system.Upregulation of alpha7 Nicotinic Receptors by Acetylcholinesterase C-Terminal Peptides.Different cholinesterase inhibitor effects on CSF cholinesterases in Alzheimer patients.The discovery of potential acetylcholinesterase inhibitors: a combination of pharmacophore modeling, virtual screening, and molecular docking studies.Butyrylcholinesterase attenuates amyloid fibril formation in vitro.Interaction of prion protein with acetylcholinesterase: potential pathobiological implications in prion diseases.Novel cholinesterase inhibitors as future effective drugs for the treatment of Alzheimer's disease.Presenilin 1 interacts with acetylcholinesterase and alters its enzymatic activity and glycosylation.Amyloid-cholinesterase interactions. Implications for Alzheimer's disease.Amyloid-β peptides act as allosteric modulators of cholinergic signalling through formation of soluble BAβACs.Increased Expression of Readthrough Acetylcholinesterase Variants in the Brains of Alzheimer's Disease Patients.Neuronal AChE splice variants and their non-hydrolytic functions: redefining a target of AChE inhibitors?Amyloid-beta-Acetylcholinesterase complexes potentiate neurodegenerative changes induced by the Abeta peptide. Implications for the pathogenesis of Alzheimer's diseaseIt all starts at the ends: multifaceted involvement of C- and N-terminally modified cholinesterases in Alzheimer's disease.Tacrine, Trolox and Tryptoline as Lead Compounds for the Design and Synthesis of Multi-target Agents for Alzheimer's Disease Therapy.A new motif in the N-terminal of acetylcholinesterase triggers amyloid-β aggregation and deposition.Cholinesterases and the fine line between poison and remedy.Elaborate ligand-based modeling coupled with QSAR analysis and in silico screening reveal new potent acetylcholinesterase inhibitors.Selective acetyl- and butyrylcholinesterase inhibitors reduce amyloid-β ex vivo activation of peripheral chemo-cytokines from Alzheimer's disease subjects: exploring the cholinergic anti-inflammatory pathway.
P2860
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P2860
Memory deficits correlating with acetylcholinesterase splice shift and amyloid burden in doubly transgenic mice.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
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2005年學術文章
@zh-hant
name
Memory deficits correlating wi ...... den in doubly transgenic mice.
@en
Memory deficits correlating wi ...... den in doubly transgenic mice.
@nl
type
label
Memory deficits correlating wi ...... den in doubly transgenic mice.
@en
Memory deficits correlating wi ...... den in doubly transgenic mice.
@nl
prefLabel
Memory deficits correlating wi ...... den in doubly transgenic mice.
@en
Memory deficits correlating wi ...... den in doubly transgenic mice.
@nl
P2093
P356
P1476
Memory deficits correlating wi ...... rden in doubly transgenic mice
@en
P2093
Amit Berson
Ella H Sklan
Linda Younkin
Stephen Brimijoin
Steven Younkin
Tina M Rees
P304
P356
10.2174/1567205054367847
P50
P577
2005-07-01T00:00:00Z