Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes.
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Atypical teratoid/rhabdoid tumors: challenges and search for solutionsDual Targeting of PDGFRα and FGFR1 Displays Synergistic Efficacy in Malignant Rhabdoid TumorsSMARCB1-mediated SWI/SNF complex function is essential for enhancer regulationEmbryonic signature distinguishes pediatric and adult rhabdoid tumors from other SMARCB1-deficient cancers.Atypical Teratoid Rhabdoid Tumor: Two Case Reports and an Analysis of Adult Cases with Implications for Pathophysiology and Treatment.Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid TumorsCNS germinomas are characterized by global demethylation, chromosomal instability and mutational activation of the Kit-, Ras/Raf/Erk- and Akt-pathways.DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma.PopNet: A Markov Clustering Approach to Study Population Genetic Structure.Quantitative phosphoproteomic analysis of acquired cancer drug resistance to pazopanib and dasatinib.Molecular Transition of an Adult Low-Grade Brain Tumor to an Atypical Teratoid/Rhabdoid Tumor Over a Time-Course of 14 Years.Loss of CDKN1C in a Recurrent Atypical Teratoid/Rhabdoid Tumor.Therapeutic Targeting of PTK7 is Cytotoxic in Atypical Teratoid Rhabdoid Tumors.A French retrospective study on clinical outcome in 102 choroid plexus tumors in children.A functional screening of the kinome identifies the Polo-like kinase 4 as a potential therapeutic target for malignant rhabdoid tumors, and possibly, other embryonal tumors of the brain.Targeting the cancer epigenome for therapy.Molecular pathology of paediatric central nervous system tumours.SMAD dependent signaling plays a detrimental role in a fly model of SMARCB1-deficiency and the biology of atypical teratoid/rhabdoid tumors.Low-grade epilepsy-associated neuroepithelial tumours - the 2016 WHO classification.Atypical teratoid rhabdoid tumor in the first year of life: the Canadian ATRT registry experience and review of the literature.The new WHO 2016 classification of brain tumors-what neurosurgeons need to know.Modeling and Targeting MYC Genes in Childhood Brain Tumors.Mammalian SWI/SNF complexes in cancer: emerging therapeutic opportunities.Integrating RNA sequencing into neuro-oncology practice.Cribriform neuroepithelial tumor: molecular characterization of a SMARCB1-deficient non-rhabdoid tumor with favorable long-term outcome.PGBD5 promotes site-specific oncogenic mutations in human tumors.Prognostic factors and survival in non-central nervous system rhabdoid tumors.A Molecular Take on Malignant Rhabdoid Tumors.BRD9 Inhibition, Alone or in Combination with Cytostatic Compounds as a Therapeutic Approach in Rhabdoid Tumors.Timing of Smarcb1 and Nf2 inactivation determines schwannoma versus rhabdoid tumor development.Arginine auxotrophic gene signature in paediatric sarcomas and brain tumours provides a viable target for arginine depletion therapies.Transcription instability in high-risk neuroblastoma is associated with a global perturbation of chromatin domains.The whole-genome landscape of medulloblastoma subtypes.RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia.Combined BRD4 and CDK9 inhibition as a new therapeutic approach in malignant rhabdoid tumors.Targeting Polo-like kinase 1 in SMARCB1 deleted atypical teratoid rhabdoid tumor.Multimodal treatments combined with gamma knife surgery for primary atypical teratoid/rhabdoid tumor of the central nervous system: a single-institute experience of 18 patients.Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling.Atypical teratoid/rhabdoid tumor in the sella turcica of an elderly female with a distinct vascular pattern and genetic alterations.Reduced histone H3 K27 trimethylation is encountered in about 50% of atypical teratoid/rhabdoid tumors (AT/RT) but is not associated with molecular subgroup status and outcome.
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P2860
Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh
2016年學術文章
@zh-hant
name
Atypical Teratoid/Rhabdoid Tum ...... Distinct Enhancer Landscapes.
@en
Atypical Teratoid/Rhabdoid Tum ...... Distinct Enhancer Landscapes.
@nl
type
label
Atypical Teratoid/Rhabdoid Tum ...... Distinct Enhancer Landscapes.
@en
Atypical Teratoid/Rhabdoid Tum ...... Distinct Enhancer Landscapes.
@nl
prefLabel
Atypical Teratoid/Rhabdoid Tum ...... Distinct Enhancer Landscapes.
@en
Atypical Teratoid/Rhabdoid Tum ...... Distinct Enhancer Landscapes.
@nl
P2093
P50
P1433
P1476
Atypical Teratoid/Rhabdoid Tum ...... Distinct Enhancer Landscapes.
@en
P2093
Amar Gajjar
Andrea Wittmann
Andreas E Kulozik
Andrey Korshunov
Anna Bertoni
Annie Huang
Carl Hermann
Christina Geörg
David Sumerauer
David T W Jones
P304
P356
10.1016/J.CCELL.2016.02.001
P50
P577
2016-02-18T00:00:00Z