Role of protein kinase C phosphorylation in rapid desensitization of metabotropic glutamate receptor 5.
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Positive allosteric modulation of metabotropic glutamate 5 (mGlu5) receptors reverses N-Methyl-D-aspartate antagonist-induced alteration of neuronal firing in prefrontal cortexOpposing effects of protein kinase C and protein kinase A on metabotropic glutamate receptor signaling: selective desensitization of the inositol trisphosphate/Ca2+ pathway by phosphorylation of the receptor-G protein-coupling domainStructural, signalling and regulatory properties of the group I metabotropic glutamate receptors: prototypic family C G-protein-coupled receptorsThe C terminus of the metabotropic glutamate receptor subtypes 2 and 7 specifies the receptor signaling pathwaysGroup I metabotropic glutamate receptors bind to protein phosphatase 1C. Mapping and modeling of interacting sequencesModulation of the neuronal dopamine transporter activity by the metabotropic glutamate receptor mGluR5 in rat striatal synaptosomes through phosphorylation mediated processes.Presynaptic m1 muscarinic receptors are necessary for mGluR long-term depression in the hippocampusRegulation of group I metabotropic glutamate receptor expression in the rat striatum and prefrontal cortex in response to amphetamine in vivoDysregulation of group-I metabotropic glutamate (mGlu) receptor mediated signalling in disorders associated with Intellectual Disability and AutismDeterminants of metabotropic glutamate receptor-5-mediated Ca2+ and inositol 1,4,5-trisphosphate oscillation frequency. Receptor density versus agonist concentration.Roles of serine/threonine phosphatases in hippocampal synaptic plasticity.Location-dependent signaling of the group 1 metabotropic glutamate receptor mGlu5.Distinct physiological roles of the Gq-coupled metabotropic glutamate receptors Co-expressed in the same neuronal populations.Post-translational modification biology of glutamate receptors and drug addictionMitochondrial reactive oxygen species are activated by mGluR5 through IP3 and activate ERK and PKA to increase excitability of amygdala neurons and pain behavior.Molecular basis for the inhibition of G protein-coupled inward rectifier K(+) channels by protein kinase CDirect effects of metabotropic glutamate receptor compounds on native and recombinant N-methyl-D-aspartate receptorsEvidence that the nucleotide exchange and hydrolysis cycle of G proteins causes acute desensitization of G-protein gated inward rectifier K+ channelsEnvironmental condition alters amphetamine self-administration: role of the MGluR₅ receptor and schedule of reinforcement.Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1).Incubation of cocaine-craving relates to glutamate over-flow within ventromedial prefrontal cortex.Regulation of synaptic transmission by ambient extracellular glutamateModulation of pyramidal cell output in the medial prefrontal cortex by mGluR5 interacting with CB1.Calmodulin dynamically regulates the trafficking of the metabotropic glutamate receptor mGluR5.Differential modulation of ethanol-induced sedation and hypnosis by metabotropic glutamate receptor antagonists in C57BL/6J mice.Deficits in ventromedial prefrontal cortex group 1 metabotropic glutamate receptor function mediate resistance to extinction during protracted withdrawal from an extensive history of cocaine self-administrationAn analog of thyrotropin-releasing hormone (TRH) is neuroprotective against glutamate-induced toxicity in fetal rat hippocampal neurons in vitroPhosphorylation of group I metabotropic glutamate receptors (mGluR1/5) in vitro and in vivoSignal transduction mechanisms underlying group I mGluR-mediated increase in frequency and amplitude of spontaneous EPSCs in the spinal trigeminal subnucleus oralis of the rat.Proteomic analysis of native metabotropic glutamate receptor 5 protein complexes reveals novel molecular constituentsRole of protein kinase C epsilon (PKCvarepsilon) in the reduction of ethanol reinforcement due to mGluR5 antagonism in the nucleus accumbens shell.Overexpression of diacylglycerol kinase η enhances Gαq-coupled G protein-coupled receptor signaling.Group 1 metabotropic glutamate receptor function and its regulation of learning and memory in the aging brainThe mGluR5 positive allosteric modulator CDPPB inhibits SO₂-induced protein radical formation and mitochondrial dysfunction through activation of Akt in mouse hippocampal HT22 cells.Pyk2 uncouples metabotropic glutamate receptor G protein signaling but facilitates ERK1/2 activation.Long-Term Activation of Group I Metabotropic Glutamate Receptors Increases Functional TRPV1-Expressing Neurons in Mouse Dorsal Root Ganglia.Calcineurin inhibitor protein (CAIN) attenuates Group I metabotropic glutamate receptor endocytosis and signaling.Phosphorylation-independent regulation of metabotropic glutamate receptor 1 signaling requires g protein-coupled receptor kinase 2 binding to the second intracellular loop.G protein-coupled receptor kinase-mediated desensitization of metabotropic glutamate receptor 1A protects against cell death.Phosphorylation and feedback regulation of metabotropic glutamate receptor 1 by calcium/calmodulin-dependent protein kinase II.
P2860
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P2860
Role of protein kinase C phosphorylation in rapid desensitization of metabotropic glutamate receptor 5.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Role of protein kinase C phosp ...... botropic glutamate receptor 5.
@en
Role of protein kinase C phosp ...... botropic glutamate receptor 5.
@nl
type
label
Role of protein kinase C phosp ...... botropic glutamate receptor 5.
@en
Role of protein kinase C phosp ...... botropic glutamate receptor 5.
@nl
prefLabel
Role of protein kinase C phosp ...... botropic glutamate receptor 5.
@en
Role of protein kinase C phosp ...... botropic glutamate receptor 5.
@nl
P1433
P1476
Role of protein kinase C phosp ...... botropic glutamate receptor 5.
@en
P2093
Gereau RW 4th
Heinemann SF
P304
P356
10.1016/S0896-6273(00)80442-0
P407
P577
1998-01-01T00:00:00Z