Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains.
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The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptideThe generation and function of soluble apoE receptors in the CNSPresenilin 1 is linked with gamma-secretase activity in the detergent solubilized stateHuman amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivoCurcumin and its derivatives: their application in neuropharmacology and neuroscience in the 21st centuryAmyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memorySilibinin prevents amyloid beta peptide-induced memory impairment and oxidative stress in miceStabilization of neurotoxic soluble beta-sheet-rich conformations of the Alzheimer's disease amyloid-beta peptideSoluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's diseaseCerebral amyloid angiopathy: amyloid beta accumulates in putative interstitial fluid drainage pathways in Alzheimer's diseaseRegulation of protein homeostasis in neurodegenerative diseases: the role of coding and non-coding genesTargeting the proper amyloid-beta neuronal toxins: a path forward for Alzheimer's disease immunotherapeuticsChronochemistry in neurodegenerationαA-crystallin peptide SDRDKFVIFLDVKHF accumulating in aging lens impairs the function of α-crystallin and induces lens protein aggregationMolecular Structure of β-Amyloid Fibrils in Alzheimer’s Disease Brain TissueMolecular Structure of Aggregated Amyloid-β: Insights from Solid-State Nuclear Magnetic ResonanceInsight of brain degenerative protein modifications in the pathology of neurodegeneration and dementia by proteomic profilingAPOE-modulated Aβ-induced neuroinflammation in Alzheimer's disease: current landscape, novel data, and future perspectiveβ-secretase inhibitor; a promising novel therapeutic drug in Alzheimer's diseaseReelin and apoE actions on signal transduction, synaptic function and memory formationBapineuzumab alters aβ composition: implications for the amyloid cascade hypothesis and anti-amyloid immunotherapyLoss of alpha7 nicotinic receptors enhances beta-amyloid oligomer accumulation, exacerbating early-stage cognitive decline and septohippocampal pathology in a mouse model of Alzheimer's disease.Orientation of tyrosine side chain in neurotoxic Aβ differs in two different secondary structures of the peptideLarge aggregates are the major soluble Aβ species in AD brain fractionated with density gradient ultracentrifugationAmyloid-β oligomer specificity mediated by the IgM isotype--implications for a specific protective mechanism exerted by endogenous auto-antibodiesAlzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons.BMS-708163 and Nilotinib restore synaptic dysfunction in human embryonic stem cell-derived Alzheimer's disease modelsDiffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxinsSoluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's diseasePET amyloid-beta imaging in preclinical Alzheimer's diseaseReversal of fragile X phenotypes by manipulation of AβPP/Aβ levels in Fmr1KO miceTGF-β induces TIAF1 self-aggregation via type II receptor-independent signaling that leads to generation of amyloid β plaques in Alzheimer's disease.Alzheimer brain-derived amyloid β-protein impairs synaptic remodeling and memory consolidation.Interactions between amyloid-β and hemoglobin: implications for amyloid plaque formation in Alzheimer's disease.Systemic catabolism of Alzheimer's Abeta40 and Abeta42.Sequence determinants of enhanced amyloidogenicity of Alzheimer A{beta}42 peptide relative to A{beta}40.Autoinsertion of soluble oligomers of Alzheimer's Abeta(1-42) peptide into cholesterol-containing membranes is accompanied by relocation of the sterol towards the bilayer surface.Biochemical and immunohistochemical analysis of an Alzheimer's disease mouse model reveals the presence of multiple cerebral Abeta assembly forms throughout life.Proteomic analysis of the amyloid precursor protein fragment C99: expression in yeast.Opposite effects of low and high doses of Abeta42 on electrical network and neuronal excitability in the rat prefrontal cortex.
P2860
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P2860
Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh-hant
name
Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains.
@en
Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains.
@nl
type
label
Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains.
@en
Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains.
@nl
prefLabel
Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains.
@en
Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains.
@nl
P2093
P356
P1476
Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains.
@en
P2093
Emmerling MR
Kasunic TC
Kirkpatrick JB
Murdoch GH
Vigo-Pelfrey C
P304
P356
10.1074/JBC.271.8.4077
P407
P577
1996-02-01T00:00:00Z