Highlight report: prediction of drug induced liver injury (DILI) with human hepatocytes in vitro.

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Highlight report: prediction of drug induced liver injury (DILI) with human hepatocytes in vitro.

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Highlight report: prediction o ...... th human hepatocytes in vitro.

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Highlight report: prediction of drug induced liver injury

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Highlight report: prediction o ...... th human hepatocytes in vitro.

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Highlight report: prediction of drug induced liver injury

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Highlight report: prediction o ...... th human hepatocytes in vitro.

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Highlight report: prediction of drug induced liver injury

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P1476

Highlight report: prediction o ...... th human hepatocytes in vitro.

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Wiebke Albrecht

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Advances in hepatic stem/progenitor cell biology

Evidence-based selection of training compounds for use in the mechanism-based integrated prediction of drug-induced liver injury in man

Cryopreserved primary hepatocytes as a constantly available in vitro model for the evaluation of human and animal drug metabolism and enzyme induction.

Toxicogenomics directory of chemically exposed human hepatocytes.

Primary hepatocytes: current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies.

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.

Hepatotoxicity of piperazine designer drugs: up-regulation of key enzymes of cholesterol and lipid biosynthesis.

Drug-induced liver injury: an overview over the most critical compounds.

Comparative analysis of 3D culture methods on human HepG2 cells.

HepaRG microencapsulated spheroids in DMSO-free culture: novel culturing approaches for enhanced xenobiotic and biosynthetic metabolism.

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s00204-017-2132-5

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scholarly article

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10.1007/S00204-017-2132-5

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2017-11-27T00:00:00Z

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1093026622

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29181616

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