Toxicogenomics directory of chemically exposed human hepatocytes.
about
A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitorsDTNI: a novel toxicogenomics data analysis tool for identifying the molecular mechanisms underlying the adverse effects of toxic compounds.Biomarker: the universe of chemically induced gene expression alterations in human hepatocyteGene expression and pathway analysis of human hepatocellular carcinoma cells treated with cadmiumPerspectives of tissues in silicoTranscriptional Regulation of Cytosolic Sulfotransferase 1C2 by Intermediates of the Cholesterol Biosynthetic Pathway in Primary Cultured Rat HepatocytesCombination of multiple neural crest migration assays to identify environmental toxicants from a proof-of-concept chemical library.Identification of transcriptome signatures and biomarkers specific for potential developmental toxicants inhibiting human neural crest cell migration.Highlight report: Erroneous sample annotation in a high fraction of publicly available genome-wide expression datasetsCharacterization of Conserved Toxicogenomic Responses in Chemically Exposed Hepatocytes across Species and Platforms.Drug-induced mitochondrial impairment in liver cells.Expression classifiers for developmental toxicants.Highlight report: New methods for quantification of bile canalicular dynamics.Therapy of hyperammonemia.Identification of carcinogens by a selected panel of DNA damage response associated genes.Hepatotoxicity of piperazine designer drugs: up-regulation of key enzymes of cholesterol and lipid biosynthesis."Watching the Detectives" report of the general assembly of the EU project DETECTIVE Brussels, 24-25 November 2015.Highlight report: Cardiotoxicity screening.Imprinting of Skin/Inflammation Homing in CD4+ T Cells Is Controlled by DNA Methylation within the Fucosyltransferase 7 Gene.Transcriptome based differentiation of harmless, teratogenetic and cytotoxic concentration ranges of valproic acid.Concepts of predictive toxicology.Highlight report: Blueprint for stem cell differentiation into liver cells.Adverse outcome pathways: opportunities, limitations and open questionsPathophysiology of cholestatic liver disease and its relevance for in vitro tests of hepatotoxicity.Possibilities and limitations of intravital imaging.Human non-parenchymal liver cells for co-cultivation systems.Integrated spatiotemporal-metabolic modelling bridges the gap between metabolism on the cellular level and organ function.From smoking guns to footprints: mining for critical events of toxicity pathways in transcriptome data.Highlight report: Launch of a large integrated European in vitro toxicology project: EU-ToxRisk.Recent developments in animal sciences.Highlight report: Interspecies extrapolation by physiologically based pharmacokinetic modeling.Highlight report: biomarkers of acetaminophen-induced liver injury.Highlight report: perspectives in stem cell research--unbiased quantification of the similarity between in vitro generated and primary hepatocytes.Highlight report: xenobiotic-metabolizing enzymes in skin models.Current research on experimental and applied animal sciences.Bile canaliculi formation and biliary transport in 3D sandwich-cultured hepatocytes in dependence of the extracellular matrix composition.Highlight report: Metabolomics in hepatotoxicity testing.Highlight report: prediction of drug induced liver injury (DILI) with human hepatocytes in vitro.Stem cells in toxicological research.Adverse outcome pathways.
P2860
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P2860
Toxicogenomics directory of chemically exposed human hepatocytes.
description
2014 nî lūn-bûn
@nan
2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Toxicogenomics directory of chemically exposed human hepatocytes.
@ast
Toxicogenomics directory of chemically exposed human hepatocytes.
@en
type
label
Toxicogenomics directory of chemically exposed human hepatocytes.
@ast
Toxicogenomics directory of chemically exposed human hepatocytes.
@en
prefLabel
Toxicogenomics directory of chemically exposed human hepatocytes.
@ast
Toxicogenomics directory of chemically exposed human hepatocytes.
@en
P2093
P2860
P50
P1476
Toxicogenomics directory of chemically exposed human hepatocytes.
@en
P2093
Adil Mardinoglu
Agata Widera
Alfons Lampen
Andreas Nüssler
Bob van de Water
Daniel Seehofer
Dimitry Spitkovsky
Dragana Mitic
Eugen Rempel
Harry van Steeg
P2860
P2888
P304
P356
10.1007/S00204-014-1400-X
P50
P577
2014-11-16T00:00:00Z