Brain region-specific enhancement of remyelination and prevention of demyelination by the CSF1R kinase inhibitor BLZ945.

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The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models.CSF1R Inhibition Reduces Microglia Proliferation, Promotes Tissue Preservation and Improves Motor Recovery After Spinal Cord Injury

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Brain region-specific enhancement of remyelination and prevention of demyelination by the CSF1R kinase inhibitor BLZ945.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年學術文章

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2018年學術文章

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name

Brain region-specific enhancem ...... CSF1R kinase inhibitor BLZ945.

@en

Brain region-specific enhancem ...... CSF1R kinase inhibitor BLZ945.

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type

Item

label

Brain region-specific enhancem ...... CSF1R kinase inhibitor BLZ945.

@en

Brain region-specific enhancem ...... CSF1R kinase inhibitor BLZ945.

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prefLabel

Brain region-specific enhancem ...... CSF1R kinase inhibitor BLZ945.

@en

Brain region-specific enhancem ...... CSF1R kinase inhibitor BLZ945.

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P1476

Brain region-specific enhancem ...... CSF1R kinase inhibitor BLZ945.

@en

P2093

Anna Neuhaus

http://www.w3.org/2001/XMLSchema#string

Derya R Shimshek

http://www.w3.org/2001/XMLSchema#string

Elisa Giorgetti

http://www.w3.org/2001/XMLSchema#string

Julien Perdoux

http://www.w3.org/2001/XMLSchema#string

Ludovic Perrot

http://www.w3.org/2001/XMLSchema#string

Mark Nash

http://www.w3.org/2001/XMLSchema#string

Nathalie Accart

http://www.w3.org/2001/XMLSchema#string

Nicolau Beckmann

http://www.w3.org/2001/XMLSchema#string

Paul Smith

http://www.w3.org/2001/XMLSchema#string

Peter Wipfli

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P2860

Depletion of microglia and inhibition of exosome synthesis halt tau propagation.

Inefficient clearance of myelin debris by microglia impairs remyelinating processes

Quantitative MRI and ultrastructural examination of the cuprizone mouse model of demyelination.

Eliminating microglia in Alzheimer's mice prevents neuronal loss without modulating amyloid-β pathology.

Therapeutic inhibition of soluble brain TNF promotes remyelination by increasing myelin phagocytosis by microglia

Neurotoxic reactive astrocytes are induced by activated microglia.

Absence of colony stimulation factor-1 receptor results in loss of microglia, disrupted brain development and olfactory deficits

Colony-stimulating factor 1 receptor signaling is necessary for microglia viability, unmasking a microglia progenitor cell in the adult brain.

Elimination of Microglia Improves Functional Outcomes Following Extensive Neuronal Loss in the Hippocampus.

CSF-1R inhibition alters macrophage polarization and blocks glioma progression.

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s40478-018-0510-8

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scholarly article

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10.1186/S40478-018-0510-8

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29448957

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5815182

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Brain region-specific enhancement of remyelination and prevention of demyelination by the CSF1R kinase inhibitor BLZ945.

about

P2860

P2860

Brain region-specific enhancement of remyelination and prevention of demyelination by the CSF1R kinase inhibitor BLZ945.

description

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P1433

P1476

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P1476

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