A core in vitro genotoxicity battery comprising the Ames test plus the in vitro micronucleus test is sufficient to detect rodent carcinogens and in vivo genotoxins.
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Evaluating microRNA profiles reveals discriminative responses following genotoxic or non-genotoxic carcinogen exposure in primary mouse hepatocytesUndetactable levels of genotoxicity of SiO2 nanoparticles in in vitro and in vivo testsIn vitro genotoxicity testing strategy for nanomaterials and the adaptation of current OECD guidelinesRetrospective analysis of the mutagenicity/genotoxicity data of the cosmetic ingredients present on the Annexes of the Cosmetic EU legislation (2000-12).Mechanistic roles of microRNAs in hepatocarcinogenesis: A study of thioacetamide with multiple doses and time-points of rats.Chromium in drinking water: sources, metabolism, and cancer risksThe Extended ToxTracker Assay Discriminates Between Induction of DNA Damage, Oxidative Stress, and Protein Misfolding.The in vitro toxicology of Swedish snus.Appropriate in vitro methods for genotoxicity testing of silver nanoparticlesChallenges in antimalarial drug discovery.The new ISSMIC database on in vivo micronucleus and its role in assessing genotoxicity testing strategies.Opportunities for an alternative integrating testing strategy for carcinogen hazard assessment?Cellular-signaling pathways unveil the carcinogenic potential of chemicals.Evaluation of four human cell lines with distinct biotransformation properties for genotoxic screening.Regulatory requirements for genotoxicity assessment of plant protection product active ingredients, impurities, and metabolites.The in vitro PIG-A gene mutation assay: mutagenicity testing via flow cytometry based on the glycosylphosphatidylinositol (GPI) status of TK6 cells.Comparative in vitro toxicity profile of electronic and tobacco cigarettes, smokeless tobacco and nicotine replacement therapy products: e-liquids, extracts and collected aerosolsA review of the carcinogenic potential of glyphosate by four independent expert panels and comparison to the IARC assessment.Genotoxicity Expert Panel review: weight of evidence evaluation of the genotoxicity of glyphosate, glyphosate-based formulations, and aminomethylphosphonic acid.Fluorescence-based recombination assay for sensitive and specific detection of genotoxic carcinogens in human cells.Testing chemical carcinogenicity by using a transcriptomics HepaRG-based model?Validation of high-throughput genotoxicity assay screening using γH2AX in-cell western assay on HepG2 cells.Comparison of in vitro test systems using bacterial and mammalian cells for genotoxicity assessment within the "health-related indication value (HRIV) concept.Evaluation of the GADD45α-GFP GreenScreen HC assay for rapid and reliable in vitro early genotoxicity screening.Global regulatory requirements for mutagenicity assessment in the registration of industrial chemicals.A transcriptomics-based in vitro assay for predicting chemical genotoxicity in vivo.The ToxTracker assay: novel GFP reporter systems that provide mechanistic insight into the genotoxic properties of chemicals.Evaluation of Safety of Arrabidaea chica Verlot (Bignoniaceae), a Plant with Healing Properties.Seven benzimidazole pesticides combined at sub-threshold levels induce micronuclei in vitro.Genotoxic bioactivation of constituents of a diesel exhaust particle extract by the human lung.Newer Approaches to Identify Potential Untoward Effects in Functional Foods.Eco- and genotoxicological assessments of two reactive textile dyes.A tripartite mode of action approach for investigating the impact of aneugens on tubulin polymerization.The Impact of Novel Assessment Methodologies in Toxicology on Green Chemistry and Chemical Alternatives.Evaluation of DNA Damage in HepG2 Cells and Mutagenicity of Garcinielliptone FC, A Bioactive Benzophenone.Antimutagenic, Antigenotoxic, and Anticytotoxic Activities of Silybum Marianum [L.] Gaertn Assessed by the Salmonella Mutagenicity Assay (Ames Test) and the Micronucleus Test in Mice Bone Marrow.Detection of genotoxicity and mutagenicity of chlorthiophos using micronucleus, chromosome aberration, sister chromatid exchange, and Ames tests.Mutagenicity and clastogenicity evaluation of metaphenoxy benzyl chloride by ames and micronucleus assays.Evaluation of the LacZ reporter assay in cryopreserved primary hepatocytes for In vitro genotoxicity testing.Exploiting microRNA and mRNA profiles generated in vitro from carcinogen-exposed primary mouse hepatocytes for predicting in vivo genotoxicity and carcinogenicity.
P2860
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P2860
A core in vitro genotoxicity battery comprising the Ames test plus the in vitro micronucleus test is sufficient to detect rodent carcinogens and in vivo genotoxins.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh-hant
name
A core in vitro genotoxicity b ...... nogens and in vivo genotoxins.
@en
A core in vitro genotoxicity b ...... nogens and in vivo genotoxins.
@nl
type
label
A core in vitro genotoxicity b ...... nogens and in vivo genotoxins.
@en
A core in vitro genotoxicity b ...... nogens and in vivo genotoxins.
@nl
prefLabel
A core in vitro genotoxicity b ...... nogens and in vivo genotoxins.
@en
A core in vitro genotoxicity b ...... nogens and in vivo genotoxins.
@nl
P2093
P1433
P1476
A core in vitro genotoxicity b ...... nogens and in vivo genotoxins.
@en
P2093
David Gatehouse
David Kirkland
Lesley Reeve
Philippe Vanparys
P356
10.1016/J.MRGENTOX.2010.12.015
P407
P577
2011-01-14T00:00:00Z