EXT1:EXT2 transfer GlcNAc to the heparan chain - Wikidata - awgldk - TriplyDB

EXT1:EXT2 transfer GlcNAc to the heparan chain

EXT1:EXT2 transfer GlcNAc to the heparan chain

http://www.wikidata.org/entity/Q50293267

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HS-GAG biosynthesis

P527

Q45317195-CA98FF9A-7D04-4285-8DB8-15DFA9CA4799

P527

EXT1:EXT2 transfer GlcNAc to the heparan chain

http://www.wikidata.org/entity/Q50293267

description

An instance of the biological ...... heparan chain in Homo sapiens

@en

biologisch proces

@nl

name

EXT1:EXT2 transfer GlcNAc to the heparan chain

@en

type

label

EXT1:EXT2 transfer GlcNAc to the heparan chain

@en

prefLabel

EXT1:EXT2 transfer GlcNAc to the heparan chain

@en

P2860

Q50293267-63C5CC7A-614D-4071-A754-8FA2DCF77830

Q50293267-DFB16AF9-ED25-42F7-A261-4D727DC3B3F2

Q50293267-F8B3860C-B68F-4BCA-B205-FF106A6CE998

P2888

Q50293267-D3EC4622-1CE7-41BC-AC6D-B73DE4FA89D5

P31

Q50293267-3A1032AE-41AC-46D4-B56D-79738A675D65

P361

Q50293267-573B754E-BC60-4DC2-A062-5C257524FBF1

P3937

Q50293267-F36CDF82-4EB4-4092-87E1-AAAB595510CD

P527

Q50293267-10581937-3D77-41F0-AE01-07DF79FF5DC6

Q50293267-7393E0A6-BC1E-471F-815C-E7DD9917BE4C

Q50293267-7BA800DA-43E0-44F0-9A0B-8BFB526742CA

Q50293267-CAE4EC15-3092-41BD-8AA1-D489AEC4A79E

Q50293267-EF94D078-98A0-4EBF-957C-44E16202AB6D

P703

Q50293267-C4FE9DC9-B97C-498F-8C9F-6BF0857235C5

P2860

The putative tumor suppressors EXT1 and EXT2 form a stable complex that accumulates in the Golgi apparatus and catalyzes the synthesis of heparan sulfate

Mutations in the EXT1 and EXT2 genes in hereditary multiple exostoses.

Diminished levels of the putative tumor suppressor proteins EXT1 and EXT2 in exostosis chondrocytes

P2888

reactome:R-HSA-2022851

P31

biological process

P361

HS-GAG biosynthesis

P3937

R-HSA-2022851

http://www.w3.org/2001/XMLSchema#string

P527

UDP N-acetyl-alpha-D-glucosamine

uridine 5'-diphosphate

P703