ATAD2 is a novel cofactor for MYC, overexpressed and amplified in aggressive tumors. - Wikidata - awgldk - TriplyDB

ATAD2 is a novel cofactor for MYC, overexpressed and amplified in aggressive tumors.

ATAD2 is a novel cofactor for MYC, overexpressed and amplified in aggressive tumors.

http://www.wikidata.org/entity/Q50335771

about

Histone recognition and large-scale structural analysis of the human bromodomain family Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2 Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells A Chemical Probe for the ATAD2 Bromodomain BET domain co-regulators in obesity, inflammation and cancer Genome-wide transcriptional reorganization associated with senescence-to-immortality switch during human hepatocellular carcinogenesis Identification of tumor suppressors and oncogenes from genomic and epigenetic features in ovarian cancer Identifying in-trans process associated genes in breast cancer by integrated analysis of copy number and expression data Identification of candidate growth promoting genes in ovarian cancer through integrated copy number and expression analysis.miR-372 down-regulates the oncogene ATAD2 to influence hepatocellular carcinoma proliferation and metastasis.HIF-1α promoted vasculogenic mimicry formation in hepatocellular carcinoma through LOXL2 up-regulation in hypoxic tumor microenvironment.Direct cooperation between androgen receptor and E2F1 reveals a common regulation mechanism for androgen-responsive genes in prostate cells.High-resolution comparative genomic hybridization of inflammatory breast cancer and identification of candidate genes.RNA-Seq analyses generate comprehensive transcriptomic landscape and reveal complex transcript patterns in hepatocellular carcinoma.Kinesin family deregulation coordinated by bromodomain protein ANCCA and histone methyltransferase MLL for breast cancer cell growth, survival, and tamoxifen resistance.MYC cofactors: molecular switches controlling diverse biological outcomes.ANCCA/ATAD2 overexpression identifies breast cancer patients with poor prognosis, acting to drive proliferation and survival of triple-negative cells through control of B-Myb and EZH2.Molecular insights into the recognition of N-terminal histone modifications by the BRPF1 bromodomain.Bromodomain coactivators in cancer, obesity, type 2 diabetes, and inflammation Integrated genomic analysis of the 8q24 amplification in endometrial cancers identifies ATAD2 as essential to MYC-dependent cancers.Small-molecular modulators of cancer-associated epigenetic mechanisms.Fragment-based screening of the bromodomain of ATAD2.Inflammatory breast cancer (IBC): clues for targeted therapies Lessons from yeast on emerging roles of the ATAD2 protein family in gene regulation and genome organization.Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.Low mir-372 expression correlates with poor prognosis and tumor metastasis in hepatocellular carcinoma Transcriptional Dynamics of Immortalized Human Mesenchymal Stem Cells during Transformation.Bioinformatics analysis of thousands of TCGA tumors to determine the involvement of epigenetic regulators in human cancer.ATAD2 as a Poor Prognostic Marker for Hepatocellular Carcinoma after Curative Resection ATAD2 overexpression links to enrichment of B-MYB-translational signatures and development of aggressive endometrial carcinoma.Abo1, a conserved bromodomain AAA-ATPase, maintains global nucleosome occupancy and organisation.Suppression of ATAD2 inhibits hepatocellular carcinoma progression through activation of p53- and p38-mediated apoptotic signaling Differential gene expression between skin and cervix induced by the E7 oncoprotein in a transgenic mouse model The Arabidopsis acetylated histone-binding protein BRAT1 forms a complex with BRP1 and prevents transcriptional silencing.Nuclear receptor coregulators as a new paradigm for therapeutic targeting.Gene expression profiling of the 8q22-24 position in human breast cancer: TSPYL5, MTDH, ATAD2 and CCNE2 genes are implicated in oncogenesis, while WISP1 and EXT1 genes may predict a risk of metastasis.Integrated genomic and epigenomic analysis of breast cancer brain metastasis Chemical synthesis of the ATAD2 bromodomain.Significance of PRO2000/ANCCA expression, a novel proliferation-associated protein in hepatocellular carcinoma.Bromodomains as therapeutic targets.

P2860

Q24310431-A039D225-136D-407A-9FD9-EF42C559BCA9 Q27696569-2F160E83-8C5C-49E1-AA71-152DCA286B07 Q27702290-840D801B-3978-4330-B0BB-0229E1442296 Q27727700-9905CE84-5819-4B4D-BF1F-93E8D8E315DD Q28269301-16C6B8DE-9D1F-4003-91F0-C455A48CAA05 Q28488081-24F44A2B-F3EA-4077-BD24-258E269D0C91 Q28741689-A3E56B75-EBA0-476B-9D0F-6116523EADD7 Q30587051-6BE7FEF2-F7D5-4977-935D-25BB7773EF2C Q33553289-D197C188-300A-4EAD-8098-D838D1082A15 Q33592473-57F28E26-925F-4A41-8968-19061B5209A2 Q33612891-16751850-3253-45EE-97CB-4349D894522E Q33636324-A4DDBF74-92A5-4996-922B-A17BB98E90A7 Q33826097-37176D07-3356-4F75-9A88-716EE90380EB Q34063655-300B8946-2051-48CB-A624-AF95DC407C04 Q34069945-BAFEC7F6-559C-49D6-8CD6-D1D11C6EC540 Q34083178-E2ABF1F0-B9A5-492A-A9D5-5A5BC8F459E6 Q34316094-69795A23-A97F-4D4B-8AB0-449253F649C3 Q34391526-23E9CAED-A45C-463F-85C4-98D57801DAF2 Q34513460-F9A3CD5D-51C3-4C64-8884-982AA99CE650 Q34580883-63E1B0F3-7B43-4E77-B004-3F7FABC76419 Q34628002-457404F4-94F8-4BAD-B0D2-8891C918CFD5 Q34631628-D0DDB299-6CE2-4988-9BEF-582F5AECD0A2 Q34754098-F6F06F79-8C0B-4B45-AD71-450BE8D4D112 Q34768072-95BA880E-CEE4-471F-A2D8-ECEAC2E7B559 Q34981653-928F7702-8219-4D7D-94E7-CE7141A26AC8 Q35233796-DC509F9A-3311-4739-8AA7-C5AE9A1B6D84 Q35610677-E6F44AC0-1D5F-41D5-BED0-99855A75926B Q35674363-A8B0466C-95DB-4087-A03D-99B1B0AB2061 Q36186943-AE6D9788-4B2C-4122-9E9F-B2D3F5EFF4EE Q36414073-371D7967-8FB5-4C08-925A-A879CEFBA1CD Q36478645-8B35278B-88D1-48CC-B896-BD54DB61F1B1 Q36561575-DB04B689-D795-49AF-8B7B-CE72A306A163 Q36772704-AC6E652C-4BFE-41DA-B9EA-2F9C4F9B679A Q36985628-AAE9C389-1D08-447A-A3AB-A933FB16C622 Q37217158-77504453-A74A-4B91-873A-CCFFC5E22DE6 Q37407194-60053B0B-18ED-464E-B56C-FF39E441E353 Q37529191-68BAD1FE-1818-40FD-9881-78F3B1855484 Q37612735-D1D85168-A534-4B43-AB6A-F80C9848E085 Q37719344-2478625F-3C65-4085-9CE1-959A8D315561 Q37935915-01628062-D9C5-4925-8664-CA3FEBE1630E

P2860

ATAD2 is a novel cofactor for MYC, overexpressed and amplified in aggressive tumors.

http://www.wikidata.org/entity/Q50335771

description

2009 nî lūn-bûn

@nan

2009年の論文

@ja

2009年学术文章

@wuu

2009年学术文章

@zh

2009年学术文章

@zh-cn

2009年学术文章

@zh-hans

2009年学术文章

@zh-my

2009年学术文章

@zh-sg

2009年學術文章

@yue

2009年學術文章

@zh-hant

name

ATAD2 is a novel cofactor for MYC, overexpressed and amplified in aggressive tumors.

@en

ATAD2 is a novel cofactor for MYC, overexpressed and amplified in aggressive tumors.

@nl

type

label

ATAD2 is a novel cofactor for MYC, overexpressed and amplified in aggressive tumors.

@en

ATAD2 is a novel cofactor for MYC, overexpressed and amplified in aggressive tumors.

@nl

prefLabel

ATAD2 is a novel cofactor for MYC, overexpressed and amplified in aggressive tumors.

@en

ATAD2 is a novel cofactor for MYC, overexpressed and amplified in aggressive tumors.

@nl

P1433

Q50335771-902F5AA3-06B8-4565-9060-B18D6E1C8CB5

P1476

Q50335771-F0FFF7AA-5DE7-4796-A17A-43CF7DB6BE10

P2093

Q50335771-2CEBA94C-C9BF-4B93-AC47-B3F7E2051F92

Q50335771-3430933A-EBA9-495F-9C1F-361A27468221

Q50335771-9E16FC37-49E4-43CB-B967-E731950D81F8

Q50335771-B35749F2-7F05-4E39-90CD-A123360B7D12

Q50335771-B95639EF-D39F-4D24-8015-54586FD1E503

Q50335771-CD770D20-3721-4D39-AC70-F6F603B1AAED

Q50335771-D832F5AF-5990-4B4C-AF64-96F5B27EAC0C

Q50335771-DA28BB6D-D1D3-46E7-92FC-8EF1AA2917F1

Q50335771-F1AA2AB2-88E6-459E-9122-A9AB914BA76C

Q50335771-F8DBFF97-4FE7-48A5-B941-52E623B60ED8

P304

Q50335771-1353B0E8-BB25-4EF0-A236-8A0E88595948

P31

Q50335771-7A6F6487-B120-464C-A40D-49D7DEFADC58

P356

Q50335771-34D10F85-5BE8-4091-810B-9EC519E0FD91

P407

Q50335771-A08D3885-F650-4875-BBAB-BB2998152859

P433

Q50335771-F3E05D46-258A-4BF9-A7F3-AA03AA9217AC

P478

Q50335771-D334F103-E0CA-4BAA-A615-DB8A95505129

P50

Q50335771-1E72E90F-7957-40E0-91D1-6EDBE4386A4C

P577

Q50335771-0F6BFE8B-8500-4F6D-B417-6228407B5CED

P698

Q50335771-7BF029BE-5209-4508-BA71-6953410384F3

P921

Q50335771-762314F4-E94A-4AEC-88CA-1BA8F2CAF8CA

P356

0008-5472.CAN-09-2131

P1433

Cancer Research

P1476

ATAD2 is a novel cofactor for MYC, overexpressed and amplified in aggressive tumors.

@en

P2093

Elena Prosperini

http://www.w3.org/2001/XMLSchema#string

Fraser McBlane

http://www.w3.org/2001/XMLSchema#string

Giovanni Pacchiana

http://www.w3.org/2001/XMLSchema#string

Jesper Christensen

http://www.w3.org/2001/XMLSchema#string

Julian Walfridsson

http://www.w3.org/2001/XMLSchema#string

Marco Ciró

http://www.w3.org/2001/XMLSchema#string

Maria Capra

http://www.w3.org/2001/XMLSchema#string

Micaela Quarto

http://www.w3.org/2001/XMLSchema#string

Paolo Nucifero

http://www.w3.org/2001/XMLSchema#string

Ursula Grazini

http://www.w3.org/2001/XMLSchema#string

P304

8491-8498

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1158/0008-5472.CAN-09-2131

http://www.w3.org/2001/XMLSchema#string

P407

P433

21

http://www.w3.org/2001/XMLSchema#string

P478

69

http://www.w3.org/2001/XMLSchema#string

P50

P577

2009-10-20T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

19843847

http://www.w3.org/2001/XMLSchema#string

P921