Activation of Tie2 by angiopoietin-1 and angiopoietin-2 results in their release and receptor internalization.
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Effects of angiopoietins-1 and -2 on the receptor tyrosine kinase Tie2 are differentially regulated at the endothelial cell surfaceAngiopoietin-1-induced ubiquitylation of Tie2 by c-Cbl is required for internalization and degradationContrasting actions of selective inhibitors of angiopoietin-1 and angiopoietin-2 on the normalization of tumor blood vesselsAnti-angiogenic alternatives to VEGF blockadeInhibition of tyrosine kinase receptor Tie2 reverts HCV-induced hepatic stellate cell activationCommon and specific effects of TIE2 mutations causing venous malformationsDifferential response of lymphatic, venous and arterial endothelial cells to angiopoietin-1 and angiopoietin-2.Dimerization of Tie2 mediated by its membrane-proximal FNIII domains.Tie1-Tie2 interactions mediate functional differences between angiopoietin ligandsAmniotic fluid angiopoietin-1, angiopoietin-2, and soluble receptor tunica interna endothelial cell kinase-2 levels and regulation in normal pregnancy and intraamniotic inflammation-induced preterm birthMolecular control of angiopoietin signalling.Primary monocytes regulate endothelial cell survival through secretion of angiopoietin-1 and activation of endothelial Tie2Angiopoietins modulate endothelial adaptation, glomerular and podocyte hypertrophy after uninephrectomy.The angiopoietin-Tie2 signaling axis in the vascular leakage of systemic inflammationLow glucose microenvironment of normal kidney cells stabilizes a subset of messengers involved in angiogenesis.Intra and extravascular transmembrane signalling of angiopoietin-1-Tie2 receptor in health and disease.Angiopoietin-4 increases permeability of blood vessels and promotes lymphatic dilation.Vasculotide reduces endothelial permeability and tumor cell extravasation in the absence of binding to or agonistic activation of Tie2.Constitutive Association of Tie1 and Tie2 with Endothelial Integrins is Functionally Modulated by Angiopoietin-1 and Fibronectin.Pulmonary arterial hypertension: a disease of tethers, SNAREs and SNAPs?Opposing actions of angiopoietin-2 on Tie2 signaling and FOXO1 activationBench-to-bedside review: Angiopoietin signalling in critical illness - a future target?Method for Dual Viral Vector Mediated CRISPR-Cas9 Gene Disruption in Primary Human Endothelial CellsTIE2 associates with caveolae and regulates caveolin-1 to promote their nuclear translocation.TIE2-mediated tyrosine phosphorylation of H4 regulates DNA damage response by recruiting ABL1.S6K2-mediated regulation of TRBP as a determinant of miRNA expression in human primary lymphatic endothelial cells.Angiopoietin-1 enhances neutrophil chemotaxis in vitro and migration in vivo through interaction with CD18 and release of CCL4.Angiopoietin-1 and angiopoietin-2 protect porcine iliac endothelial cells from human antibody-mediated complement-dependent cytotoxicity through phosphatidylinositide 3-kinase/AKT pathway activation.Endothelial glycocalyx breakdown is mediated by angiopoietin-2.Connection of pericyte-angiopoietin-Tie-2 system in diabetic retinopathy: friend or foe?Bioactive scaffolds for engineering vascularized cardiac tissues.Angiopoietin/Tie2 signaling transforms capillaries into venules primed for leukocyte trafficking in airway inflammation.Amelioration of sepsis by TIE2 activation-induced vascular protection.Ligand-independent Tie2 dimers mediate kinase activity stimulated by high dose angiopoietin-1.Laminar shear inhibits tubule formation and migration of endothelial cells by an angiopoietin-2 dependent mechanismBlockade of angiopoietin-2/Tie2 signaling pathway specifically promotes inflammation-induced angiogenesis in mouse cornea.Yes-associated protein regulates endothelial cell contact-mediated expression of angiopoietin-2.The synthetic tie2 agonist peptide vasculotide protects against vascular leakage and reduces mortality in murine abdominal sepsis.Preliminary evidence of sustained expression of angiopoietin-2 during monocyte differentiation in chronic hepatitis C.Cytoplasmic provenance of STAT3 and PY-STAT3 in the endolysosomal compartments in pulmonary arterial endothelial and smooth muscle cells: implications in pulmonary arterial hypertension.
P2860
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P2860
Activation of Tie2 by angiopoietin-1 and angiopoietin-2 results in their release and receptor internalization.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Activation of Tie2 by angiopoi ...... and receptor internalization.
@en
Activation of Tie2 by angiopoi ...... and receptor internalization.
@nl
type
label
Activation of Tie2 by angiopoi ...... and receptor internalization.
@en
Activation of Tie2 by angiopoi ...... and receptor internalization.
@nl
prefLabel
Activation of Tie2 by angiopoi ...... and receptor internalization.
@en
Activation of Tie2 by angiopoi ...... and receptor internalization.
@nl
P2093
P356
P1476
Activation of Tie2 by angiopoi ...... and receptor internalization.
@en
P2093
Daniel J Dumont
Elena Bogdanovic
Vicky P K H Nguyen
P304
P356
10.1242/JCS.03077
P407
P577
2006-08-08T00:00:00Z