Mass spectrometric analysis of the endogenous type I interleukin-1 (IL-1) receptor signaling complex formed after IL-1 binding identifies IL-1RAcP, MyD88, and IRAK-4 as the stable components.
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Deconstructing innate immune signaling in myelodysplastic syndromesThe structural pathway of interleukin 1 (IL-1) initiated signaling reveals mechanisms of oncogenic mutations and SNPs in inflammation and cancerDistribution of interleukin-1 receptor complex at the synaptic membrane driven by interleukin-1β and NMDA stimulationStructural dynamic analysis of apo and ATP-bound IRAK4 kinaseThreonine 66 in the death domain of IRAK-1 is critical for interaction with signaling molecules but is not a target site for autophosphorylation.Interleukin-7 compartmentalizes its receptor signaling complex to initiate CD4 T lymphocyte response.Molecular evolution and structural features of IRAK family members.Heme oxygenase-1 protects rat liver against warm ischemia/reperfusion injury via TLR2/TLR4-triggered signaling pathways.Protein phosphatase 2A and neutral sphingomyelinase 2 regulate IRAK-1 protein ubiquitination and degradation in response to interleukin-1betaGeneration and Characterization of Mice Expressing a Conditional Allele of the Interleukin-1 Receptor Type 1.Signaling organelles of the innate immune system.Defining the subcellular sites of innate immune signal transductionTrans-system mechanisms against ischemic myocardial injury.Anti-inflammatory effects of Bifidobacterium longum subsp infantis secretions on fetal human enterocytes are mediated by TLR-4 receptorsApoptosis signaling pathways in osteoarthritis and possible protective role of melatonin.An oligomeric signaling platform formed by the Toll-like receptor signal transducers MyD88 and IRAK-4.EGF mediates calcium-activated chloride channel activation in the human bronchial epithelial cell line 16HBE14o-: involvement of tyrosine kinase p60c-src.Penehyclidine ameliorates acute lung injury by inhibiting Toll-like receptor 2/4 expression and nuclear factor-κB activationGlaucoma is associated with plasmin proteolytic activation mediated through oxidative inactivation of neuroserpin.Interleukin (IL) 1beta induction of IL-6 is mediated by a novel phosphatidylinositol 3-kinase-dependent AKT/IkappaB kinase alpha pathway targeting activator protein-1.Two human MYD88 variants, S34Y and R98C, interfere with MyD88-IRAK4-myddosome assembly.Identification of critical residues of the MyD88 death domain involved in the recruitment of downstream kinases.IL1R1:IL1:IL1RAP binds MYD88 homodimerIL1R1:IL1:IL1RAP:MYD88 homodimer binds IRAK4Inhibition of interleukin-1 receptor-associated kinase 1 (IRAK1) as a therapeutic strategy
P2860
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P2860
Mass spectrometric analysis of the endogenous type I interleukin-1 (IL-1) receptor signaling complex formed after IL-1 binding identifies IL-1RAcP, MyD88, and IRAK-4 as the stable components.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Mass spectrometric analysis of ...... AK-4 as the stable components.
@en
Mass spectrometric analysis of ...... AK-4 as the stable components.
@nl
type
label
Mass spectrometric analysis of ...... AK-4 as the stable components.
@en
Mass spectrometric analysis of ...... AK-4 as the stable components.
@nl
prefLabel
Mass spectrometric analysis of ...... AK-4 as the stable components.
@en
Mass spectrometric analysis of ...... AK-4 as the stable components.
@nl
P2093
P2860
P1476
Mass spectrometric analysis of ...... AK-4 as the stable components.
@en
P2093
Constantinos Brikos
Jeremy Saklatvala
Luke A J O'Neill
Robin Wait
Shajna Begum
P2860
P304
P356
10.1074/MCP.M600455-MCP200
P577
2007-05-15T00:00:00Z