Isolation of an active step I spliceosome and composition of its RNP core.
about
Cwc24p is a general Saccharomyces cerevisiae splicing factor required for the stable U2 snRNP binding to primary transcriptsIdentification of novel NPRAP/δ-catenin-interacting proteins and the direct association of NPRAP with dynamin 2The human Pat1b protein: a novel mRNA deadenylation factor identified by a new immunoprecipitation techniqueMolecular architecture of the human Prp19/CDC5L complexThe RNA polymerase II C-terminal domain promotes splicing activation through recruitment of a U2AF65-Prp19 complexCwc2 and its human homologue RBM22 promote an active conformation of the spliceosome catalytic centreThe crystal structure of PPIL1 bound to cyclosporine A suggests a binding mode for a linear epitope of the SKIP proteinFunctional organization of the Sm core in the crystal structure of human U1 snRNPIsolation and characterization of post-splicing lariat-intron complexesDirect interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choiceEpigenetic principles and mechanisms underlying nervous system functions in health and diseaseModulating splicing with small molecular inhibitors of the spliceosomeThe nuts and bolts of the endogenous spliceosomeThe organization and contribution of helicases to RNA splicingNew insights into the spliceosome by single molecule fluorescence microscopyAge-related nuclear translocation of P2X6 subunit modifies splicing activity interacting with splicing factor 3A1A Novel Protein-Protein Interaction in the RES (REtention and Splicing) ComplexStructure and function of an RNase H domain at the heart of the spliceosomeStructure of the yeast Pml1 splicing factor and its integration into the RES complexStructural model of the p14/SF3b155{middle dot}branch duplex complexCancer-relevant Splicing Factor CAPERα Engages the Essential Splicing Factor SF3b155 in a Specific Ternary ComplexThe conserved ubiquitin-like protein Hub1 plays a critical role in splicing in human cellsCryo-EM structure of the spliceosome immediately after branchingThe RNA binding protein Cwc2 interacts directly with the U6 snRNA to link the nineteen complex to the spliceosome during pre-mRNA splicingThe DExD/H-box ATPase Prp2p destabilizes and proofreads the catalytic RNA core of the spliceosome.Splicing factor Cwc22 is required for the function of Prp2 and for the spliceosome to escape from a futile pathway.CEF1/CDC5 alleles modulate transitions between catalytic conformations of the spliceosome.A systematic characterization of Cwc21, the yeast ortholog of the human spliceosomal protein SRm300.Organization of Plasmodium falciparum spliceosomal core complex and role of arginine methylation in its assemblyContribution of DEAH-box protein DHX16 in human pre-mRNA splicingZFP36L1 and ZFP36L2 control LDLR mRNA stability via the ERK-RSK pathwayThe 35S U5 snRNP Is Generated from the Activated Spliceosome during In vitro SplicingOocyte-specific inactivation of Omcg1 leads to DNA damage and c-Abl/TAp63-dependent oocyte death associated with dramatic remodeling of ovarian somatic cellsA large intrinsically disordered region in SKIP and its disorder-order transition induced by PPIL1 binding revealed by NMROmcg1 is critically required for mitosis in rapidly dividing mouse intestinal progenitors and embryonic stem cells.Spliceosome Structure and FunctionMechanisms of alternative splicing regulation: insights from molecular and genomics approachesIdentification of a small molecule inhibitor that stalls splicing at an early step of spliceosome activation.Malleable ribonucleoprotein machine: protein intrinsic disorder in the Saccharomyces cerevisiae spliceosome.The role of exon sequences in C complex spliceosome structure
P2860
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P2860
Isolation of an active step I spliceosome and composition of its RNP core.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Isolation of an active step I spliceosome and composition of its RNP core.
@en
Isolation of an active step I spliceosome and composition of its RNP core.
@nl
type
label
Isolation of an active step I spliceosome and composition of its RNP core.
@en
Isolation of an active step I spliceosome and composition of its RNP core.
@nl
prefLabel
Isolation of an active step I spliceosome and composition of its RNP core.
@en
Isolation of an active step I spliceosome and composition of its RNP core.
@nl
P2093
P921
P356
P1433
P1476
Isolation of an active step I spliceosome and composition of its RNP core.
@en
P2093
Henning Urlaub
Maria Anokhina
Sergey Bessonov
P2888
P304
P356
10.1038/NATURE06842
P407
P577
2008-03-05T00:00:00Z
P6179
1022307264