The transcription factor GATA6 enables self-renewal of colon adenoma stem cells by repressing BMP gene expression.
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Wnt signaling in cancer stem cells and colon cancer metastasisAdrenocortical zonation, renewal, and remodelingToying with fate: Redirecting the differentiation of adrenocortical progenitor cells into gonadal-like tissueTNF-insulin crosstalk at the transcription factor GATA6 is revealed by a model that links signaling and transcriptomic data tensors.Integration of microenvironmental and stress signaling antagonizes colorectal cancer progression.MicroRNA-506 suppresses growth and metastasis of oral squamous cell carcinoma via targeting GATA6.Inosine modifications in human tRNAs are incorporated at the precursor tRNA level.Up-regulated NRIP2 in colorectal cancer initiating cells modulates the Wnt pathway by targeting RORβ.miR-124 targets GATA6 to suppress cholangiocarcinoma cell invasion and metastasis.GATA factors in endocrine neoplasiaThe characterization of an intestine-like genomic signature maintained during Barrett's-associated adenocarcinogenesis reveals an NR5A2-mediated promotion of cancer cell survival.BMP restricts stemness of intestinal Lgr5+ stem cells by directly suppressing their signature genes.Small genomic insertions form enhancers that misregulate oncogenesBMP signaling and its paradoxical effects in tumorigenesis and dissemination.Understanding macrophage diversity at the ontogenic and transcriptomic levels.Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling.The acinar regulator Gata6 suppresses KrasG12V-driven pancreatic tumorigenesis in mice.Self-renewal molecular mechanisms of colorectal cancer stem cells.Isolation, identification, and characterization of cancer stem cells: A review.Gata6 promotes hair follicle progenitor cell renewal by genome maintenance during proliferation.GATA6 regulates EMT and tumour dissemination, and is a marker of response to adjuvant chemotherapy in pancreatic cancer.Isolation of Human Colon Stem Cells Using Surface Expression of PTK7.REG4 is a transcriptional target of GATA6 and is essential for colorectal tumorigenesis.Three-Dimensional Spatiotemporal Modeling of Colon Cancer Organoids Reveals that Multimodal Control of Stem Cell Self-Renewal is a Critical Determinant of Size and Shape in Early Stages of Tumor Growth.ANGPTL2 expression in the intestinal stem cell niche controls epithelial regeneration and homeostasis.lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/β-catenin signaling.Functional Transcriptomics in Diverse Intestinal Epithelial Cell Types Reveals Robust MicroRNA Sensitivity in Intestinal Stem Cells to Microbial Status.Id2 controls specification of Lgr5+ intestinal stem cell progenitors during gut development.In vitro culture and phenotypic and molecular characterization of gastric stem cells from human stomach.β-catenin, leucine-rich repeat-containing G protein-coupled receptor 5 and GATA-binding factor 6 are associated with the normal mucosa-adenoma-adenocarcinoma sequence of colorectal tumorigenesis.Snail regulates BMP and TGFβ pathways to control the differentiation status of glioma-initiating cells.The TGFβ-signaling pathway and colorectal cancer: associations between dysregulated genes and miRNAs.DJ-1 promotes colorectal cancer progression through activating PLAGL2/Wnt/BMP4 axis
P2860
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P2860
The transcription factor GATA6 enables self-renewal of colon adenoma stem cells by repressing BMP gene expression.
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2014 nî lūn-bûn
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
@zh-hans
2014年学术文章
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2014年学术文章
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name
The transcription factor GATA6 ...... epressing BMP gene expression.
@en
The transcription factor GATA6 ...... epressing BMP gene expression.
@nl
type
label
The transcription factor GATA6 ...... epressing BMP gene expression.
@en
The transcription factor GATA6 ...... epressing BMP gene expression.
@nl
prefLabel
The transcription factor GATA6 ...... epressing BMP gene expression.
@en
The transcription factor GATA6 ...... epressing BMP gene expression.
@nl
P2093
P2860
P50
P356
P1433
P1476
The transcription factor GATA6 ...... repressing BMP gene expression
@en
P2093
Alexandre Calon
Ana Silvina Nacht
Anna Abuli
Elisa Montagni
Gavin Whissell
Peter Jung
P2860
P2888
P304
P356
10.1038/NCB2992
P50
P577
2014-06-22T00:00:00Z