A Functional Role for Aβ in Metal Homeostasis? N-Truncation and High-Affinity Copper Binding.

A Functional Role for Aβ in Metal Homeostasis? N-Truncation and High-Affinity Copper Binding.

Item
http://www.wikidata.org/entity/Q50578585
Numerical Simulations Reveal Randomness of Cu(II) Induced Aβ Peptide Dimerization under Conditions Present in Glutamatergic SynapsesThe Case for Abandoning Therapeutic Chelation of Copper Ions in Alzheimer's DiseaseMammalian Metallothionein-3: New Functional and Structural InsightsTruncated Amyloid-β(11-40/42) from Alzheimer Disease Binds Cu2+ with a Femtomolar Affinity and Influences Fiber Assembly.Histidine availability is decisive in ROS-mediated cytotoxicity of copper complexes of Aβ1-16 peptide.Histidine-Rich Oligopeptides To Lessen Copper-Mediated Amyloid-β Toxicity.Drastic effect of the peptide sequence on the copper-binding properties of tripeptides and the electrochemical behaviour of their copper(II) complexes.A Trishistidine Pseudopeptide with Ability to Remove Both CuΙ and CuΙΙ from the Amyloid-β Peptide and to Stop the Associated ROS Formation.Resistance of Cu(Aβ4-16) to Copper Capture by Metallothionein-3 Supports a Function for the Aβ4-42 Peptide as a Synaptic Cu(II) Scavenger.Free Superoxide is an Intermediate in the Production of H2O2 by Copper(I)-Aβ Peptide and O2.Cysteine and glutathione trigger the Cu-Zn swap between Cu(ii)-amyloid-β4-16 peptide and Zn7-metallothionein-3.Copper binding and redox chemistry of the Aβ16 peptide and its variants: insights into determinants of copper-dependent reactivity.N-terminal Cu Binding Motifs Xxx-Zzz-His (ATCUN) and Xxx-His and their derivatives: Chemistry, Biology and Medicinal Applications.Environmental and dietary exposure to copper and its cellular mechanisms linking to Alzheimer disease.Role of Copper in the Onset of Alzheimer's Disease Compared to Other Metals.Copper Binding Features of Tropomyosin-Receptor-Kinase-A Fragment: Clue for Neurotrophic Factors and Metals LinkNeurotoxicity Linked to Dysfunctional Metal Ion Homeostasis and Xenobiotic Metal Exposure: Redox Signaling and Oxidative Stress
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A Functional Role for Aβ in Metal Homeostasis? N-Truncation and High-Affinity Copper Binding.

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http://www.wikidata.org/entity/Q50578585
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
@zh-hans
2015年学术文章
@zh-my
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2015年學術文章
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2015年學術文章
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name
A Functional Role for Aβ in Me ...... High-Affinity Copper Binding.
@en
A Functional Role for Aβ in Me ...... High-Affinity Copper Binding.
@nl
type
label
A Functional Role for Aβ in Me ...... High-Affinity Copper Binding.
@en
A Functional Role for Aβ in Me ...... High-Affinity Copper Binding.
@nl
prefLabel
A Functional Role for Aβ in Me ...... High-Affinity Copper Binding.
@en
A Functional Role for Aβ in Me ...... High-Affinity Copper Binding.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
A Functional Role for Aβ in Me ...... d High-Affinity Copper Binding
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698