Poly(ADP-ribose) is required for spindle assembly and structure.
about
Investigation of PARP-1, PARP-2, and PARG interactomes by affinity-purification mass spectrometryWhole genome functional analysis identifies novel components required for mitotic spindle integrity in human cells.Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progressionPhase transition of spindle-associated protein regulate spindle apparatus assemblyThe macro domain is an ADP-ribose binding moduleNuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going?The structure of human ADP-ribosylhydrolase 3 (ARH3) provides insights into the reversibility of protein ADP-ribosylationPleiotropic cellular functions of PARP1 in longevity and aging: genome maintenance meets inflammationTankyrase inhibition impairs directional migration and invasion of lung cancer cells by affecting microtubule dynamics and polarity signals.Structure of mouse ADP-ribosylhydrolase 3 (mARH3)NuMA is a major acceptor of poly(ADP-ribosyl)ation by tankyrase 1 in mitosis.Early spindle assembly in Drosophila embryos: role of a force balance involving cytoskeletal dynamics and nuclear mechanics.Dynamic partitioning of mitotic kinesin-5 cross-linkers between microtubule-bound and freely diffusing states.Fast microtubule dynamics in meiotic spindles measured by single molecule imaging: evidence that the spindle environment does not stabilize microtubules.Lamin B counteracts the kinesin Eg5 to restrain spindle pole separation during spindle assemblyA nuclear-derived proteinaceous matrix embeds the microtubule spindle apparatus during mitosisQuantitative analysis of the binding affinity of poly(ADP-ribose) to specific binding proteins as a function of chain lengthPrometaphase spindle maintenance by an antagonistic motor-dependent force balance made robust by a disassembling lamin-B envelope.The 68-kDa telomeric repeat binding factor 1 (TRF1)-associated protein (TAP68) interacts with and recruits TRF1 to the spindle pole during mitosisA selective eradication of human nonhereditary breast cancer cells by phenanthridine-derived polyADP-ribose polymerase inhibitorsMolecular Insights into Poly(ADP-ribose) Recognition and Processing.PolyADP-ribosylation is required for pronuclear fusion during postfertilization in mice.Directly probing the mechanical properties of the spindle and its matrix.PARP-1 regulates resistance of pancreatic cancer to TRAIL therapy.A membranous spindle matrix orchestrates cell division.PIASy mediates SUMO-2/3 conjugation of poly(ADP-ribose) polymerase 1 (PARP1) on mitotic chromosomes.Roles of polymerization dynamics, opposed motors, and a tensile element in governing the length of Xenopus extract meiotic spindlesPoly(ADP-ribose) glycohydrolase is a component of the FMRP-associated messenger ribonucleoparticles.Clickable NAD analogues for labeling substrate proteins of poly(ADP-ribose) polymerases.Family-wide analysis of poly(ADP-ribose) polymerase activityA phenanthrene derived PARP inhibitor is an extra-centrosomes de-clustering agent exclusively eradicating human cancer cellsSelective small molecule inhibition of poly(ADP-ribose) glycohydrolase (PARG).Chromatin composition is changed by poly(ADP-ribosyl)ation during chromatin immunoprecipitation.DNA repair and personalized breast cancer therapyRapid elimination of the histone variant MacroH2A from somatic cell heterochromatin after nuclear transferXenopus tropicalis egg extracts provide insight into scaling of the mitotic spindlePoly(ADP-ribose) polymerase-2 contributes to the fidelity of male meiosis I and spermiogenesisAnalysis of poly(ADP-Ribose) polymerases in Arabidopsis telomere biology.Microtubule assembly in meiotic extract requires glycogen.Eg5 steps it up!
P2860
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P2860
Poly(ADP-ribose) is required for spindle assembly and structure.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Poly(ADP-ribose) is required for spindle assembly and structure.
@en
type
label
Poly(ADP-ribose) is required for spindle assembly and structure.
@en
prefLabel
Poly(ADP-ribose) is required for spindle assembly and structure.
@en
P2093
P2860
P356
P1433
P1476
Poly(ADP-ribose) is required for spindle assembly and structure.
@en
P2093
Myron K Jacobson
Paul Chang
Timothy J Mitchison
P2860
P2888
P304
P356
10.1038/NATURE03061
P407
P577
2004-12-01T00:00:00Z
P5875
P6179
1017251954