A human physiologically based pharmacokinetic model for trichloroethylene and its metabolites, trichloroacetic acid and free trichloroethanol.
about
In silico toxicology: simulating interaction thresholds for human exposure to mixtures of trichloroethylene, tetrachloroethylene, and 1,1,1-trichloroethane.Urinary levels of trichloroacetic acid, a disinfection by-product in chlorinated drinking water, in a human reference population.Glu504Lys Single Nucleotide Polymorphism of Aldehyde Dehydrogenase 2 Gene and the Risk of Human DiseasesThe implications of using a physiologically based pharmacokinetic (PBPK) model for pesticide risk assessmentNeurotoxic and pharmacokinetic responses to trichloroethylene as a function of exposure scenario.Metabolism of trichloroethyleneHuman variability and susceptibility to trichloroethylenePhysiologically based pharmacokinetic models for trichloroethylene and its oxidative metabolites.A real-time in-vivo method for studying the percutaneous absorption of volatile chemicals.Trichloroethylene biotransformation and its role in mutagenicity, carcinogenicity and target organ toxicity.Metabolism and tissue distribution of orally administered trichloroethylene in male and female rats: identification of glutathione- and cytochrome P-450-derived metabolites in liver, kidney, blood, and urine.Issues in the pharmacokinetics of trichloroethylene and its metabolites.Multiple effects of trichloroethanol on calcium handling in rat submandibular acinar cells.Development of a human Physiologically Based Pharmacokinetic (PBPK) Toolkit for environmental pollutants.Application of physiologically based pharmacokinetic models in chemical risk assessment.Applying mode-of-action and pharmacokinetic considerations in contemporary cancer risk assessments: an example with trichloroethylene.Trichloroethylene and Its Oxidative Metabolites Enhance the Activated State and Th1 Cytokine Gene Expression in Jurkat CellsRelationship between vapor intrusion and human exposure to trichloroethyleneRole of exhaled breath biomarkers in environmental health science.Trichloroethylene: Mechanistic, epidemiologic and other supporting evidence of carcinogenic hazard.Occupational exposure to solvents and risk of head and neck cancer in women: a population-based case-control study in FranceTrichloroethylene risk assessment: a review and commentary.Performance Assessment and Translation of Physiologically Based Pharmacokinetic Models from acslX™ to Berkeley Madonna™, MATLAB®, and R language: Oxytetracycline and Gold Nanoparticles as Case Examples.In vivo effects of naproxen, salicylic acid, and valproic acid on the pharmacokinetics of trichloroethylene and metabolites in rats.Micronucleus induction by oxidative metabolites of trichloroethylene in cultured human peripheral blood lymphocytes: a comparative genotoxicity study.Translational research to develop a human PBPK models tool kit-volatile organic compounds (VOCs).Moving from external exposure concentration to internal dose: duration extrapolation based on physiologically based pharmacokinetic derived estimates of internal dose.Postnatal growth considerations for PBPK modeling.[Health evaluation of trichloroethylene in indoor air : communication from the German ad-hoc working group on indoor guidelines of the Indoor Air Hygiene Committee and of the states' supreme health authorities].Feasibility of metabolic parameter estimation in pharmacokinetic models of carbon tetrachloride exposure in rats1
P2860
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P2860
A human physiologically based pharmacokinetic model for trichloroethylene and its metabolites, trichloroacetic acid and free trichloroethanol.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
A human physiologically based ...... cid and free trichloroethanol.
@en
A human physiologically based ...... cid and free trichloroethanol.
@nl
type
label
A human physiologically based ...... cid and free trichloroethanol.
@en
A human physiologically based ...... cid and free trichloroethanol.
@nl
prefLabel
A human physiologically based ...... cid and free trichloroethanol.
@en
A human physiologically based ...... cid and free trichloroethanol.
@nl
P2093
P356
P1476
A human physiologically based ...... cid and free trichloroethanol.
@en
P2093
P304
P356
10.1006/TAAP.1998.8486
P577
1998-10-01T00:00:00Z