Cbl-b mediates TGFβ sensitivity by downregulating inhibitory SMAD7 in primary T cells.
about
Ubiquitous points of control over regulatory T cells.Cbl-b-deficient mice express alterations in trafficking-related molecules but retain sensitivity to the multiple sclerosis therapeutic agent, FTY720.TCR signaling intensity controls CD8+ T cell responsiveness to TGF-β.Notch prevents transforming growth factor-beta-assisted epithelial-mesenchymal transition in cultured limbal progenitor cells through the induction of Smad7.Modulation of Immune Cell Functions by the E3 Ligase Cbl-b.Regulation of TGF-β Family Signaling by Inhibitory Smads.Cblb-deficient T cells are less susceptible to PD-L1-mediated inhibition.Prolonged exposure to extracellular lumican restrains pancreatic adenocarcinoma growth.Lys63-polyubiquitination by the E3 ligase casitas B-lineage lymphoma-b (Cbl-b) modulates peripheral regulatory T cell tolerance in patients with systemic lupus erythematosus.Immune Regulation by Ubiquitin Tagging as Checkpoint Code.Regulation of Lymphatic GM-CSF Expression by the E3 Ubiquitin Ligase Cbl-b
P2860
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P2860
Cbl-b mediates TGFβ sensitivity by downregulating inhibitory SMAD7 in primary T cells.
description
2013 nî lūn-bûn
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2013年の論文
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name
Cbl-b mediates TGFβ sensitivity by downregulating inhibitory SMAD7 in primary T cells.
@en
Cbl-b mediates TGFβ sensitivity by downregulating inhibitory SMAD7 in primary T cells.
@nl
type
label
Cbl-b mediates TGFβ sensitivity by downregulating inhibitory SMAD7 in primary T cells.
@en
Cbl-b mediates TGFβ sensitivity by downregulating inhibitory SMAD7 in primary T cells.
@nl
prefLabel
Cbl-b mediates TGFβ sensitivity by downregulating inhibitory SMAD7 in primary T cells.
@en
Cbl-b mediates TGFβ sensitivity by downregulating inhibitory SMAD7 in primary T cells.
@nl
P2093
P2860
P50
P356
P1476
Cbl-b mediates TGFβ sensitivity by downregulating inhibitory SMAD7 in primary T cells
@en
P2093
Christa Pfeifhofer-Obermair
Gottfried Baier
Marlies Meisel
Natascha Hermann-Kleiter
Reinhard Hinterleitner
Thomas Gruber
P2860
P304
P356
10.1093/JMCB/MJT017
P577
2013-05-24T00:00:00Z