Key bioanalytical measurements for antibody-drug conjugate development: PK/PD modelers' perspective.
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World Antibody-Drug Conjugate Summit, October 15-16, 2013, San Francisco, CA.A priori prediction of tumor payload concentrations: preclinical case study with an auristatin-based anti-5T4 antibody-drug conjugateProtective effect of different anti-rabies virus VHH constructs against rabies disease in mice.Application of Pharmacokinetic-Pharmacodynamic Modeling and Simulation for Antibody-Drug Conjugate Development.Integration of bioanalytical measurements using PK-PD modeling and simulation: implications for antibody-drug conjugate development.Measurement and Mathematical Characterization of Cell-Level Pharmacokinetics of Antibody-Drug Conjugates: A Case Study with Trastuzumab-vc-MMAE.Immunogenicity of antibody drug conjugates: bioanalytical methods and monitoring strategy for a novel therapeutic modality.Antibody-drug conjugate bioanalysis using LB-LC-MS/MS hybrid assays: strategies, methodology and correlation to ligand-binding assays.
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P2860
Key bioanalytical measurements for antibody-drug conjugate development: PK/PD modelers' perspective.
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Key bioanalytical measurements ...... : PK/PD modelers' perspective.
@en
Key bioanalytical measurements ...... : PK/PD modelers' perspective.
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type
label
Key bioanalytical measurements ...... : PK/PD modelers' perspective.
@en
Key bioanalytical measurements ...... : PK/PD modelers' perspective.
@nl
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Key bioanalytical measurements ...... : PK/PD modelers' perspective.
@en
Key bioanalytical measurements ...... : PK/PD modelers' perspective.
@nl
P2093
P2860
P356
P1433
P1476
Key bioanalytical measurements ...... : PK/PD modelers' perspective.
@en
P2093
Alison Betts
Dhaval K Shah
Frank Barletta
Steven Hansel
P2860
P304
P356
10.4155/BIO.13.78
P577
2013-05-01T00:00:00Z