Development of High Affinity and High Specificity Inhibitors of Matrix Metalloproteinase 14 through Computational Design and Directed Evolution.
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Spondyloarthritis: Matrix Metalloproteinasesas Biomarkers of Pathogenesis and Response to Tumor Necrosis Factor (TNF) Inhibitors.Therapeutic Potential of Matrix Metalloproteinase Inhibition in Breast Cancer.Strategies to Target Matrix Metalloproteinases as Therapeutic Approach in Cancer.Three unrelated protease inhibitors enhance accumulation of pharmaceutical recombinant proteins in N. benthamiana.Converting a broad matrix metalloproteinase family inhibitor into a specific inhibitor of MMP-9 and MMP-14.A bi-specific inhibitor targeting IL-17A and MMP-9 reduces invasion and motility in MDA-MB-231 cells.Targeting intracellular MMPs efficiently inhibits tumor metastasis and angiogenesis.Targeting the MMP-14/MMP-2/integrin αβ axis with multispecific N-TIMP2-based antagonists for cancer therapyCombinatorial engineering of N-TIMP2 variants that selectively inhibit MMP9 and MMP14 function in the cellNovel Arginine-containing Macrocyclic MMP Inhibitors: Synthesis, Tc-labeling, and Evaluation
P2860
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P2860
Development of High Affinity and High Specificity Inhibitors of Matrix Metalloproteinase 14 through Computational Design and Directed Evolution.
description
2017 nî lūn-bûn
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2017年の論文
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2017年学术文章
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name
Development of High Affinity a ...... Design and Directed Evolution.
@en
Development of High Affinity a ...... Design and Directed Evolution.
@nl
type
label
Development of High Affinity a ...... Design and Directed Evolution.
@en
Development of High Affinity a ...... Design and Directed Evolution.
@nl
prefLabel
Development of High Affinity a ...... Design and Directed Evolution.
@en
Development of High Affinity a ...... Design and Directed Evolution.
@nl
P2093
P2860
P356
P1476
Development of High Affinity a ...... Design and Directed Evolution.
@en
P2093
Itay Cohen
Jason Shirian
Julia M Shifman
Moran Grossman
Valeria Arkadash
Yuval Horev
P2860
P304
P356
10.1074/JBC.M116.756718
P407
P577
2017-01-13T00:00:00Z