about
Molecular Basis of a Million-Fold Affinity Maturation Process in a Protein–Protein InteractionComputational Design of the Affinity and Specificity of a Therapeutic T Cell ReceptorCrystal structure of Streptococcus pyogenes EndoS, an immunomodulatory endoglycosidase specific for human IgG antibodiesFactorbook.org: a Wiki-based database for transcription factor-binding data generated by the ENCODE consortiumPrediction of homoprotein and heteroprotein complexes by protein docking and template-based modeling: A CASP-CAPRI experimentCommunity-wide assessment of protein-interface modeling suggests improvements to design methodology.How structural adaptability exists alongside HLA-A2 bias in the human αβ TCR repertoireStructure-based design of a T-cell receptor leads to nearly 100-fold improvement in binding affinity for pepMHC.Accelerating protein docking in ZDOCK using an advanced 3D convolution libraryCommunity-wide evaluation of methods for predicting the effect of mutations on protein-protein interactions.Cutting edge: Evidence for a dynamically driven T cell signaling mechanism.Updates to the Integrated Protein-Protein Interaction Benchmarks: Docking Benchmark Version 5 and Affinity Benchmark Version 2.High-throughput sequencing analysis of post-liver transplantation HCV E2 glycoprotein evolution in the presence and absence of neutralizing monoclonal antibody.Structural basis for penetration of the glycan shield of hepatitis C virus E2 glycoprotein by a broadly neutralizing human antibody.Blind prediction of interfacial water positions in CAPRIVaccination with cancer- and HIV infection-associated endogenous retrotransposable elements is safe and immunogenicStructural Basis for Clonal Diversity of the Public T Cell Response to a Dominant Human Cytomegalovirus Epitope.The Missing Heritability in T1D and Potential New Targets for Prevention.Global mapping of antibody recognition of the hepatitis C virus E2 glycoprotein: Implications for vaccine design.Hepatitis C virus vaccine candidates inducing protective neutralizing antibodies.Viral evasion and challenges of hepatitis C virus vaccine development.Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors.A generalized framework for computational design and mutational scanning of T-cell receptor binding interfaces.A flexible docking approach for prediction of T cell receptor-peptide-MHC complexes.Combinations of affinity-enhancing mutations in a T cell receptor reveal highly nonadditive effects within and between complementarity determining regions and chains.Structure-Based Design of Hepatitis C Virus Vaccines that Elicit Neutralizing Antibody Responses to a Conserved Epitope.Protein-protein docking: overview and performance analysis.Affinity maturation of a broadly neutralizing human monoclonal antibody that prevents acute hepatitis C virus infection in mice.Performance of ZDOCK and ZRANK in CAPRI rounds 13-19.Designing a B Cell-Based Vaccine against a Highly Variable Hepatitis C Virus.ATLAS: A database linking binding affinities with structures for wild-type and mutant TCR-pMHC complexes.Performance of ZDOCK and IRAD in CAPRI rounds 28-34.ZRANK: reranking protein docking predictions with an optimized energy function.Backbone flexibility of CDR3 and immune recognition of antigens.Computational Reprogramming of T Cell Antigen Receptor Binding Properties.Integrating statistical pair potentials into protein complex prediction.M-ZDOCK: a grid-based approach for Cn symmetric multimer docking.The performance of ZDOCK and ZRANK in rounds 6-11 of CAPRI.Computational Modeling of Hepatitis C Virus Envelope Glycoprotein Structure and Recognition.Mapping Determinants of Virus Neutralization and Viral Escape for Rational Design of a Hepatitis C Virus Vaccine.
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Brian G Pierce
@ast
Brian G Pierce
@en
Brian G Pierce
@es
Brian G Pierce
@nl
Brian G Pierce
@sl
type
label
Brian G Pierce
@ast
Brian G Pierce
@en
Brian G Pierce
@es
Brian G Pierce
@nl
Brian G Pierce
@sl
prefLabel
Brian G Pierce
@ast
Brian G Pierce
@en
Brian G Pierce
@es
Brian G Pierce
@nl
Brian G Pierce
@sl
P106
P21
P31
P496
0000-0003-4821-0368