Novel histone deacetylase 6 (HDAC6) selective inhibitors: a patent evaluation (WO2014181137).

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Histone deacetylase 6 inhibition reduces cysts by decreasing cAMP and Ca2+ in knock-out mouse models of polycystic kidney disease.A Novel Dual HDAC6 and Tubulin Inhibitor, MPT0B451, Displays Anti-tumor Ability in Human Cancer Cells in Vitro and in Vivo.

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Novel histone deacetylase 6 (HDAC6) selective inhibitors: a patent evaluation (WO2014181137).

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http://www.wikidata.org/entity/Q51188342

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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name

Novel histone deacetylase 6 (H ...... ent evaluation (WO2014181137).

@en

Novel histone deacetylase 6

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type

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Novel histone deacetylase 6 (H ...... ent evaluation (WO2014181137).

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Novel histone deacetylase 6

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Novel histone deacetylase 6 (H ...... ent evaluation (WO2014181137).

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Novel histone deacetylase 6

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P1476

Novel histone deacetylase 6 (H ...... ent evaluation (WO2014181137).

@en

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Muriel Cuendet

http://www.w3.org/2001/XMLSchema#string

Philippe Bertrand

http://www.w3.org/2001/XMLSchema#string

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The role of HDAC6 in cancer

The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress

A novel small molecule hydroxamate preferentially inhibits HDAC6 activity and tumour growth

HDAC6 is a specific deacetylase of peroxiredoxins and is involved in redox regulation

Histone deacetylase 6 binds polyubiquitin through its zinc finger (PAZ domain) and copurifies with deubiquitinating enzymes

HDAC inhibitors as anti-inflammatory agents

HDAC2 negatively regulates memory formation and synaptic plasticity.

HDAC6 as a target for neurodegenerative diseases: what makes it different from the other HDACs?

HDAC6 inhibitor blocks amyloid beta-induced impairment of mitochondrial transport in hippocampal neurons

HDAC6 regulates mitochondrial transport in hippocampal neurons

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229-236

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scholarly article

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10.1080/13543776.2017.1282945

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English

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http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

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Claudia Simoes-Pires

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2017-01-16T00:00:00Z

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28092474

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Novel histone deacetylase 6 (HDAC6) selective inhibitors: a patent evaluation (WO2014181137).

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P2860

P2860

Novel histone deacetylase 6 (HDAC6) selective inhibitors: a patent evaluation (WO2014181137).

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