Variants of the TCF7L2 gene are associated with beta cell dysfunction and confer an increased risk of type 2 diabetes mellitus in the ULSAM cohort of Swedish elderly men.
about
The genetic susceptibility to type 2 diabetes may be modulated by obesity status: implications for association studies.Association between TCF7L2 gene polymorphisms and susceptibility to type 2 diabetes mellitus: a large Human Genome Epidemiology (HuGE) review and meta-analysisGenotype and tissue-specific effects on alternative splicing of the transcription factor 7-like 2 gene in humansTCF7L2 is a master regulator of insulin production and processing.TCF7L2, dietary carbohydrate, and risk of type 2 diabetes in US women.Association of 18 confirmed susceptibility loci for type 2 diabetes with indices of insulin release, proinsulin conversion, and insulin sensitivity in 5,327 nondiabetic Finnish men.Preliminary report: No association between TCF7L2 rs7903146 and euglycemic-clamp-derived insulin sensitivity in a mixed-age cohort.Molecular Analysis of a Genetic Variants Panel Related to Nutrients and Metabolism: Association with Susceptibility to Gestational Diabetes and Cardiometabolic Risk in Affected WomenAssociation between transcription factor 7-like 2 rs7903146 polymorphism and diabetic retinopathy in type 2 diabetes mellitus: A meta-analysis.Wnt3a regulates proliferation, apoptosis and function of pancreatic NIT-1 beta cells via activation of IRS2/PI3K signaling.Role of the single nucleotide polymorphism rs7903146 of TCF7L2 in inducing nonsense-mediated decay.Using multiple genetic variants as instrumental variables for modifiable risk factors.Effects of TCF7L2 polymorphisms on obesity in European populations.Association of type 2 diabetes susceptibility genes (TCF7L2, SLC30A8, PCSK1 and PCSK2) and proinsulin conversion in a Chinese population.Meta-analysis of association between TCF7L2 polymorphism rs7903146 and type 2 diabetes mellitus.TCF7L2 correlation in both insulin secretion and postprandial insulin sensitivity.
P2860
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P2860
Variants of the TCF7L2 gene are associated with beta cell dysfunction and confer an increased risk of type 2 diabetes mellitus in the ULSAM cohort of Swedish elderly men.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Variants of the TCF7L2 gene ar ...... cohort of Swedish elderly men.
@en
Variants of the TCF7L2 gene ar ...... cohort of Swedish elderly men.
@nl
type
label
Variants of the TCF7L2 gene ar ...... cohort of Swedish elderly men.
@en
Variants of the TCF7L2 gene ar ...... cohort of Swedish elderly men.
@nl
prefLabel
Variants of the TCF7L2 gene ar ...... cohort of Swedish elderly men.
@en
Variants of the TCF7L2 gene ar ...... cohort of Swedish elderly men.
@nl
P2093
P1433
P1476
Variants of the TCF7L2 gene ar ...... cohort of Swedish elderly men.
@en
P2093
A Dahlgren
A-C Syvänen
B Zethelius
K Jensevik
P2888
P356
10.1007/S00125-007-0746-5
P577
2007-07-06T00:00:00Z