Transcription factor Pax5 activates the chromatin of key genes involved in B cell signaling, adhesion, migration, and immune function.
about
ZNF423 and ZNF521: EBF1 Antagonists of Potential Relevance in B-Lymphoid MalignanciesHeparan sulfate proteoglycans in the control of B cell development and the pathogenesis of multiple myelomaMaintenance of β-cell maturity and plasticity in the adult pancreas: developmental biology concepts in adult physiologyThe transcription factor Pax5 regulates its target genes by recruiting chromatin-modifying proteins in committed B cellsA chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mousePolarity protein Par3 controls B-cell receptor dynamics and antigen extraction at the immune synapse.Identification of hub genes and regulatory factors of glioblastoma multiforme subgroups by RNA-seq data analysisIdentification of pax6-dependent gene regulatory networks in the mouse lens.From hematopoietic progenitors to B cells: mechanisms of lineage restriction and commitmentPax5 loss imposes a reversible differentiation block in B-progenitor acute lymphoblastic leukemia.Gene transcript abundance profiles distinguish Kawasaki disease from adenovirus infectionSex-specific gene expression in the BXD mouse liverGenome-wide analysis of Pax8 binding provides new insights into thyroid functions.Regulation of DNA replication within the immunoglobulin heavy-chain locus during B cell commitmentA recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia.The generation of antibody-secreting plasma cells.Genome-wide expression analysis in Down syndrome: insight into immunodeficiency.Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors.HDAC7 is a repressor of myeloid genes whose downregulation is required for transdifferentiation of pre-B cells into macrophages.Histone acetyltransferase p300 acetylates Pax5 and strongly enhances Pax5-mediated transcriptional activityPeripheral natural killer cell maturation depends on the transcription factor AiolosPAX5 activates the transcription of the human telomerase reverse transcriptase gene in B cells.Dissecting teleost B cell differentiation using transcription factors.The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection.An incoherent regulatory network architecture that orchestrates B cell diversification in response to antigen signaling.Ebf1 or Pax5 haploinsufficiency synergizes with STAT5 activation to initiate acute lymphoblastic leukemia.Dynamic changes in binding of immunoglobulin heavy chain 3' regulatory region to protein factors during class switching.Dominant-negative mechanism of leukemogenic PAX5 fusions.The orchestration of mammalian tissue morphogenesis through a series of coherent feed-forward loops.Quantitative modeling of the terminal differentiation of B cells and mechanisms of lymphomagenesis.Uncovering MicroRNA Regulatory Hubs that Modulate Plasma Cell DifferentiationA Network Model to Describe the Terminal Differentiation of B CellsExpression of essential B cell development genes in horses with common variable immunodeficiency.Bone marrow transcriptome and epigenome profiles of equine common variable immunodeficiency patients unveil block of B lymphocyte differentiation.Single-cell analysis of early B-lymphocyte development suggests independent regulation of lineage specification and commitment in vivo.Oct2 enhances antibody-secreting cell differentiation through regulation of IL-5 receptor alpha chain expression on activated B cells.All-or-none suppression of B cell terminal differentiation by environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin.Mechanisms of epigenetic deregulation in lymphoid neoplasms.Pax5 and linker histone H1 coordinate DNA methylation and histone modifications in the 3' regulatory region of the immunoglobulin heavy chain locus.Cloning of genes involved in chromosomal translocations by high-resolution single nucleotide polymorphism genomic microarray.
P2860
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P2860
Transcription factor Pax5 activates the chromatin of key genes involved in B cell signaling, adhesion, migration, and immune function.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Transcription factor Pax5 acti ...... igration, and immune function.
@en
Transcription factor Pax5 acti ...... igration, and immune function.
@nl
type
label
Transcription factor Pax5 acti ...... igration, and immune function.
@en
Transcription factor Pax5 acti ...... igration, and immune function.
@nl
prefLabel
Transcription factor Pax5 acti ...... igration, and immune function.
@en
Transcription factor Pax5 acti ...... igration, and immune function.
@nl
P2093
P1433
P1476
Transcription factor Pax5 acti ...... igration, and immune function.
@en
P2093
Alexandra Schebesta
Georg A Busslinger
Giorgia Salvagiotto
Shane McManus
P356
10.1016/J.IMMUNI.2007.05.019
P407
P577
2007-07-19T00:00:00Z