Acute myeloid leukemia bearing t(7;11)(p15;p15) is a distinct cytogenetic entity with poor outcome and a distinct mutation profile: comparative analysis of 493 adult patients.
about
Rare Cytogenetic Abnormalities and Alteration of microRNAs in Acute Myeloid Leukemia and Response to TherapyIn vitro transformation of primary human CD34+ cells by AML fusion oncogenes: early gene expression profiling reveals possible drug target in AMLChromosome t(7;11)(p15;p15) translocation in acute myeloid leukemia coexisting with multilineage dyspoiesis and mutations in NRAS and WT1: A case report and literature reviewNUP98/NSD1 and FLT3/ITD coexpression is more prevalent in younger AML patients and leads to induction failure: a COG and SWOG report.Dynein Light Chain 1 (DYNLT1) Interacts with Normal and Oncogenic Nucleoporins.NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insightsAnalysis of the Hox epigenetic code.Expression of Leukemia-Associated Nup98 Fusion Proteins Generates an Aberrant Nuclear Envelope Phenotype.POU1F1 is a novel fusion partner of NUP98 in acute myeloid leukemia with t(3;11)(p11;p15).A Novel Translocation Involving RUNX1 and HOXA Gene Clusters in a Case of Acute Myeloid Leukemia with t(7;21)(p15;q22).Engrailed homeobox transcription factors as potential markers and targets in cancer.EN2: a novel prostate cancer biomarker.NUP98 Fusion Proteins Interact with the NSL and MLL1 Complexes to Drive Leukemogenesis.NUP98 is rearranged in 3.8% of pediatric AML forming a clinical and molecular homogenous group with a poor prognosis.NUP98-HOXA9 bearing therapy-related myeloid neoplasm involves myeloid-committed cell and induces HOXA5, EVI1, FLT3, and MEIS1 expression.Common and overlapping oncogenic pathways contribute to the evolution of acute myeloid leukemias.HoxA9 regulated Bcl-2 expression mediates survival of myeloid progenitors and the severity of HoxA9-dependent leukemia.NUP98-NSD1 gene fusion and its related gene expression signature are strongly associated with a poor prognosis in pediatric acute myeloid leukemia.A rare but specific subset of adult AML patients can be defined by the cytogenetically cryptic NUP98-NSD1 fusion gene.Outcomes after allogeneic hematopoietic stem cell transplantation in patients with acute myeloid leukemia harboring t(7;11)(p15;p15).Recurrent Cytogenetic Abnormalities in Acute Myeloid Leukemia.HOXD10 expression in human breast cancer.The oncogenic fusion protein CBFB-SMMHC downregulates CD48 to evade NK cell recognition.Acute myeloid leukemiaNucleoporin Gene Fusions and Hematopoietic Malignancies
P2860
Q26771425-21734D5E-F564-4810-9F1C-A10FD530BF55Q28475341-524092EC-7C58-43DC-B0F5-179F1134F26CQ33684901-EC0BCFB7-5AFC-4EAE-8AD3-D32AA1C85312Q34318490-5442E52A-BA19-46A3-83C6-74D915788185Q34806322-AA6FC05D-6833-4E17-A08F-B2F3473E9706Q35608150-0933A3D3-D523-480A-9475-98581B961E56Q35926749-1F740597-DA01-4167-A195-D7A4DDA0705EQ35975179-807D3408-8866-47C3-A585-5CD91B4C8F79Q36597216-C680869C-3FC4-4D6D-A5D4-7F4F8A640FD1Q37279191-30ADAD9C-731C-46CD-82B7-0252CF8CDDE1Q38080336-400ED067-BBC0-4D61-8047-9C00236FF7CCQ38165246-A907C380-EAB0-4C24-BC19-5C85DA606B63Q39152206-9A1DC4F5-D203-482D-B61F-BD1EA41656CAQ40557194-D17C3ACE-D844-4F1A-BF0B-20791727B5A7Q41291574-A4CE2DDC-2EB8-4DAE-92FA-A716D33EFE8CQ42010591-0A250369-7825-477F-B89A-D99FFEA848E0Q42770287-4DE2FCAC-4A15-4DFD-8ECB-85F301C97E75Q44123939-BB842F31-CAA9-4F6A-9513-858A517682AAQ45378151-4BFF8F27-0A00-48B2-A886-0571569157E6Q49733444-51E0E34E-0235-4EA4-9524-D7BE25F16298Q52817300-91383A86-BF67-47F1-AF6C-F4AD61E13C87Q54196355-96D4C5B1-8EAC-466F-9BA0-52B0A79D7C51Q55322172-533F8E75-B582-45EF-A69B-544221080D24Q58481761-90BA6CBC-AE9D-4E9C-9043-C4ED96562080Q59072645-A0F63392-AA74-4F9C-A8FE-528CD11A98B1
P2860
Acute myeloid leukemia bearing t(7;11)(p15;p15) is a distinct cytogenetic entity with poor outcome and a distinct mutation profile: comparative analysis of 493 adult patients.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
Acute myeloid leukemia bearing t
@nl
Acute myeloid leukemia bearing ...... nalysis of 493 adult patients.
@en
type
label
Acute myeloid leukemia bearing t
@nl
Acute myeloid leukemia bearing ...... nalysis of 493 adult patients.
@en
prefLabel
Acute myeloid leukemia bearing t
@nl
Acute myeloid leukemia bearing ...... nalysis of 493 adult patients.
@en
P2093
P2860
P356
P1433
P1476
Acute myeloid leukemia bearing ...... nalysis of 493 adult patients.
@en
P2093
P2860
P2888
P304
P356
10.1038/LEU.2009.25
P577
2009-02-19T00:00:00Z