A pharmacologically validated, high-capacity, functional thallium flux assay for the human Ether-à-go-go related gene potassium channel.
about
Discovery, characterization, and structure-activity relationships of an inhibitor of inward rectifier potassium (Kir) channels with preference for Kir2.3, Kir3.x, and Kir7.1.Electrophysiological study of V535M hERG mutation of LQT2.Discovery of Selective Small Molecule ROMK Inhibitors as Potential New Mechanism Diuretics.Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13.Identification and characterization of a compound that protects cardiac tissue from human Ether-à-go-go-related gene (hERG)-related drug-induced arrhythmiasHigh-throughput fluorescent-based NKCC functional assay in adherent epithelial cells.Investigation of miscellaneous hERG inhibition in large diverse compound collection using automated patch-clamp assay.Galectin-3 Regulates Atrial Fibrillation Remodeling and Predicts Catheter Ablation OutcomesApproaches for probing allosteric interactions at 7 transmembrane spanning receptors.Predicting drug-induced QT prolongation and torsades de pointes: a review of preclinical endpoint measures.Targeting cardiac potassium channels for state-of-the-art drug discovery.The importance of being profiled: improving drug candidate safety and efficacy using ion channel profiling.hERG ion channel pharmacology: cell membrane liposomes in porous-supported lipid bilayers compared with whole-cell patch-clamping.Investigation of Cardiovascular Effects of Tetrahydro-β-carboline sstr3 antagonists.hERG drug response measured in droplet bilayers.Thallium Flux Assay for Measuring the Activity of Monovalent Cation Channels and Transporters.Challenges in the Development of Functional Assays of Membrane Proteins.
P2860
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P2860
A pharmacologically validated, high-capacity, functional thallium flux assay for the human Ether-à-go-go related gene potassium channel.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
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name
A pharmacologically validated, ...... elated gene potassium channel.
@en
A pharmacologically validated, ...... elated gene potassium channel.
@nl
type
label
A pharmacologically validated, ...... elated gene potassium channel.
@en
A pharmacologically validated, ...... elated gene potassium channel.
@nl
prefLabel
A pharmacologically validated, ...... elated gene potassium channel.
@en
A pharmacologically validated, ...... elated gene potassium channel.
@nl
P2093
P356
P1476
A pharmacologically validated, ...... elated gene potassium channel.
@en
P2093
Andrew M Swensen
Brande S Thomas
Gregory J Kaczorowski
John P Felix
Kelli Solly
Laszlo Kiss
Maria L Garcia
Rodolfo J Haedo
William A Schmalhofer
P304
P356
10.1089/ADT.2010.0351
P577
2010-12-01T00:00:00Z