Histologic subtypes of hepatoblastoma are characterized by differential canonical Wnt and Notch pathway activation in DLK+ precursors.
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Multi-organ Mapping of Cancer RiskHepatoblastoma: A Need for Cell Lines and Tissue Banks to Develop Targeted Drug TherapiesTowards an international pediatric liver tumor consensus classification: proceedings of the Los Angeles COG liver tumors symposiumβ-Catenin Signaling and Roles in Liver Homeostasis, Injury, and TumorigenesisGene expression profiling reveals signatures characterizing histologic subtypes of hepatoblastoma and global deregulation in cell growth and survival pathwaysConcomitant downregulation of the imprinted genes DLK1 and MEG3 at 14q32.2 by epigenetic mechanisms in urothelial carcinomaComplete surgical resection is curative for children with hepatoblastoma with pure fetal histology: a report from the Children's Oncology Group.Calpain induces N-terminal truncation of β-catenin in normal murine liver development: diagnostic implications in hepatoblastomas.Unifying cancer genetics.The evolving roles of canonical WNT signaling in stem cells and tumorigenesis: implications in targeted cancer therapiesRegulatory network analysis of genes and microRNAs in human hepatoblastoma.Loss of EGFR-ASAP1 signaling in metastatic and unresectable hepatoblastoma.Implementation of next generation sequencing into pediatric hematology-oncology practice: moving beyond actionable alterations.Emerging gene-directed anti-tumor strategies against human hepatoblastoma.Current issues and controversies in the classification of pediatric hepatocellular tumors.Current and future management strategies for relapsed or progressive hepatoblastoma.Genetics and epigenetics of hepatoblastoma.The complex role of NOTCH receptors and their ligands in the development of hepatoblastoma, cholangiocarcinoma and hepatocellular carcinoma.The Childhood Solid Tumor Network: A new resource for the developmental biology and oncology research communities.HGF/c-Met related activation of β-catenin in hepatoblastoma.Novel Advances in Understanding of Molecular Pathogenesis of Hepatoblastoma: A Wnt/β-Catenin Perspective.A Brief Report of Immunohistochemical Markers to Identify Aggressive Hepatoblastoma.Pharmacological inhibition of beta-catenin in hepatoblastoma cells.Genomic analysis of hepatoblastoma identifies distinct molecular and prognostic subgroups.Pure fetal histology subtype was associated with better prognosis of children with hepatoblastoma: A Chinese population-based study.Prognostic roles of pathology markers immunoexpression and clinical parameters in Hepatoblastoma.Genetic ablation of β-catenin inhibits the proliferative phenotype of mouse liver adenomas.Activation of β-catenin and Yap1 in human hepatoblastoma and induction of hepatocarcinogenesis in mice.Selective poisoning of Ctnnb1-mutated hepatoma cells in mouse liver tumors by a single application of acetaminophen.RLIM suppresses hepatocellular carcinogenesis by up-regulating p15 and p21.Quantification of glypican 3, β-catenin and claudin-1 protein expression in hepatoblastoma and paediatric hepatocellular carcinoma by colour deconvolution.Mutant CTNNB1 and histological heterogeneity define metabolic subtypes of hepatoblastoma.Germline APC mutations in hepatoblastoma.Reduced salivary gland size and increased presence of epithelial progenitor cells in DLK1-deficient mice.SALL4 is a marker of the embryonal subtype of hepatoblastoma.Integrating Molecular Testing in the Diagnosis and Management of Children with Thyroid Lesions.Generation of pediatric liver cancer patient-derived xenograft platforms for pediatric liver cancer: A critical stage in the development of anticancer treatments.Exome sequencing of hepatoblastoma reveals novel mutations and cancer genes in the Wnt pathway and ubiquitin ligase complex.A Monoclonal Antibody to Human DLK1 Reveals Differential Expression in Cancer and Absence in Healthy Tissues
P2860
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P2860
Histologic subtypes of hepatoblastoma are characterized by differential canonical Wnt and Notch pathway activation in DLK+ precursors.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
Histologic subtypes of hepatob ...... activation in DLK+ precursors.
@en
Histologic subtypes of hepatob ...... activation in DLK+ precursors.
@nl
type
label
Histologic subtypes of hepatob ...... activation in DLK+ precursors.
@en
Histologic subtypes of hepatob ...... activation in DLK+ precursors.
@nl
prefLabel
Histologic subtypes of hepatob ...... activation in DLK+ precursors.
@en
Histologic subtypes of hepatob ...... activation in DLK+ precursors.
@nl
P2093
P1433
P1476
Histologic subtypes of hepatob ...... activation in DLK+ precursors.
@en
P2093
Adekunle M Adesina
David M Hoang
Dolores López-Terrada
Joseph Pulliam
Judith Margolin
Milton J Finegold
Preethi H Gunaratne
Toni-Ann Mistretta
Yummy Nguyen
P304
P356
10.1016/J.HUMPATH.2008.07.022
P407
P577
2009-02-05T00:00:00Z