Cytogenetic and genetic evidence supports a role for the kainate-type glutamate receptor gene, GRIK4, in schizophrenia and bipolar disorder.
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The genetics of bipolar disorder: genome ‘hot regions,’ genes, new potential candidates and future directionsThe genetics of bipolar disorderKainate receptors coming of age: milestones of two decades of researchA common variant in the 3'UTR of the GRIK4 glutamate receptor gene affects transcript abundance and protects against bipolar disorderRole of nucleus accumbens glutamatergic plasticity in drug addictionInteracting haplotypes at the NPAS3 locus alter risk of schizophrenia and bipolar disorderAssociation analysis of 94 candidate genes and schizophrenia-related endophenotypes.A gain-of-function mutation in the GRIK2 gene causes neurodevelopmental deficitsGlutamatergic synaptic dysregulation in schizophrenia: therapeutic implications.The GluK4 kainate receptor subunit regulates memory, mood, and excitotoxic neurodegeneration.Analysis of 94 candidate genes and 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia.Complete Disruption of the Kainate Receptor Gene Family Results in Corticostriatal Dysfunction in Mice.A novel analytical framework for dissecting the genetic architecture of behavioral symptoms in neuropsychiatric disorders.Pharmacogenetics of major depression: insights from level 1 of the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial.Detecting local haplotype sharing and haplotype associationGlutamatergic modulators: the future of treating mood disorders?GRIK4 polymorphism and its association with antidepressant response in depressed patients: a meta-analysisUnderstanding the pharmacogenetics of selective serotonin reuptake inhibitors.Population-based linkage analysis of schizophrenia and bipolar case-control cohorts identifies a potential susceptibility locus on 19q13.A cytogenetic abnormality and rare coding variants identify ABCA13 as a candidate gene in schizophrenia, bipolar disorder, and depressionModerate exercise and chronic stress produce counteractive effects on different areas of the brain by acting through various neurotransmitter receptor subtypes: a hypothesis.Genetics in schizophrenia: where are we and what next?Novel glutamatergic agents for major depressive disorder and bipolar disorder.Expression profiling in neuropsychiatric disorders: emphasis on glutamate receptors in bipolar disorderGenetic ablation of the GluK4 kainate receptor subunit causes anxiolytic and antidepressant-like behavior in mice.Ionotropic GABA and Glutamate Receptor Mutations and Human Neurologic Diseases.Physiology and pathology of calcium signaling in the brain.Therapeutic potential of kainate receptors.de novo interstitial deletions at the 11q23.3-q24.2 regionNeurotransmission and bipolar disorder: a systematic family-based association study.Ionotropic glutamate receptors & CNS disorders.Role of glutamate in schizophrenia: integrating excitatory avenues of research.The role of the tripartite glutamatergic synapse in the pathophysiology and therapeutics of mood disorders.Can the role of genetic factors in schizophrenia be enlightened by studies of candidate gene mutant mice behaviour?Emerging Synaptic Molecules as Candidates in the Etiology of Neurological Disorders.Neurodegeneration in schizophrenia.Progress in defining the biological causes of schizophrenia.Pharmacogenetics of antidepressant drugs: an update after almost 20 years of research.Disorders and borders: psychiatric genetics and nosology.The emerging role of dopamine-glutamate interaction and of the postsynaptic density in bipolar disorder pathophysiology: Implications for treatment.
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P2860
Cytogenetic and genetic evidence supports a role for the kainate-type glutamate receptor gene, GRIK4, in schizophrenia and bipolar disorder.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
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2006年學術文章
@zh-hant
name
Cytogenetic and genetic eviden ...... ophrenia and bipolar disorder.
@en
Cytogenetic and genetic eviden ...... ophrenia and bipolar disorder.
@nl
type
label
Cytogenetic and genetic eviden ...... ophrenia and bipolar disorder.
@en
Cytogenetic and genetic eviden ...... ophrenia and bipolar disorder.
@nl
prefLabel
Cytogenetic and genetic eviden ...... ophrenia and bipolar disorder.
@en
Cytogenetic and genetic eviden ...... ophrenia and bipolar disorder.
@nl
P2093
P2860
P356
P1433
P1476
Cytogenetic and genetic eviden ...... ophrenia and bipolar disorder.
@en
P2093
A Christoforou
D H R Blackwood
D J Porteous
M P Malloy
P A Thomson
S W Morris
P2860
P2888
P304
P356
10.1038/SJ.MP.4001867
P407
P577
2006-07-04T00:00:00Z