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Structure, Dynamics, and Allosteric Potential of Ionotropic Glutamate Receptor N-Terminal DomainsNeto1 and Neto2: auxiliary subunits that determine key properties of native kainate receptorsCalcium-permeable channels in plant cellsRedefining the classification of AMPA-selective ionotropic glutamate receptorsComputational study of synthetic agonist ligands of ionotropic glutamate receptorsMolecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4Molecular Mechanism of Flop Selectivity and Subsite Recognition for an AMPA Receptor Allosteric Modulator: Structures of GluA2 and GluA3 in Complexes with PEPADynamics and allosteric potential of the AMPA receptor N-terminal domainThermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2Structural analysis of the positive AMPA receptor modulators CX516 and Me-CX516 in complex with the GluA2 ligand-binding domainMolecular recognition of two 2,4-syn-functionalized (S)-glutamate analogues by the kainate receptor GluK3 ligand binding domainAbnormally increased surface expression of AMPA receptors in the cerebellum, cortex and striatum of Cln3(-/-) miceDomoic acid as a developmental neurotoxin.Structure and organization of heteromeric AMPA-type glutamate receptorsRole of the Ion Channel Extracellular Collar in AMPA Receptor GatingMutant β-III spectrin causes mGluR1α mislocalization and functional deficits in a mouse model of spinocerebellar ataxia type 5.AMPA receptor regulation at the mRNA and protein level in rat primary cortical culturesTranslational PK-PD modelling of molecular target modulation for the AMPA receptor positive allosteric modulator Org 26576.Recurrent distal 7q11.23 deletion including HIP1 and YWHAG identified in patients with intellectual disabilities, epilepsy, and neurobehavioral problems.The importance of the excitatory amino acid transporter 3 (EAAT3)The human synaptic vesicle protein, SV2A, functions as a galactose transporter in Saccharomyces cerevisiae.Acute BDNF treatment upregulates GluR1-SAP97 and GluR2-GRIP1 interactions: implications for sustained AMPA receptor expression.AMPA receptor potentiators: from drug design to cognitive enhancementAltered sensitivity of cerebellar granule cells to glutamate receptor overactivation in the Cln3(Δex7/8)-knock-in mouse model of juvenile neuronal ceroid lipofuscinosis.Structure of an agonist-bound ionotropic glutamate receptorCooperative Dynamics of Intact AMPA and NMDA Glutamate Receptors: Similarities and Subfamily-Specific Differences.Therapeutic potential of kainate receptors.Probing Intersubunit Interfaces in AMPA-subtype Ionotropic Glutamate Receptors.Atomistic mechanism for the activation and desensitization of an AMPA-subtype glutamate receptorGating reaction mechanism of neuronal NMDA receptors.Excitatory amino acid transporters as potential drug targets.Channelopathies linked to plasma membrane phosphoinositides.Modes of glutamate receptor gating.P2X receptors as drug targets.The multifaceted subunit interfaces of ionotropic glutamate receptors.Neurochemical and electrical modulation of the locus coeruleus: contribution to CO2drive to breathe.Structure and gating of tetrameric glutamate receptors.Retour aux sources: defining the structural basis of glutamate receptor activation.Differential Expression of AMPA Subunits Induced by NMDA Intrahippocampal Injection in Rats.Ion channel therapeutics for pain.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Ionotropic glutamate receptors & CNS disorders.
@en
Ionotropic glutamate receptors & CNS disorders.
@nl
type
label
Ionotropic glutamate receptors & CNS disorders.
@en
Ionotropic glutamate receptors & CNS disorders.
@nl
prefLabel
Ionotropic glutamate receptors & CNS disorders.
@en
Ionotropic glutamate receptors & CNS disorders.
@nl
P2860
P1476
Ionotropic glutamate receptors & CNS disorders
@en
P2093
Derek Bowie
P2860
P304
P356
10.2174/187152708784083821
P50
P577
2008-04-01T00:00:00Z