Spindle orientation bias in gut epithelial stem cell compartments is lost in precancerous tissue.
about
Molecular mechanisms controlling asymmetric and symmetric self-renewal of cancer stem cellsConnections between cadherin-catenin proteins, spindle misorientation, and cancerThe central role of muscle stem cells in regenerative failure with agingMaintaining tissue homeostasis: dynamic control of somatic stem cell activityAsymmetric distribution of histones during Drosophila male germline stem cell asymmetric divisionsThe many faces and functions of β-cateninUnderstanding epithelial homeostasis in the intestine: An old battlefield of ideas, recent breakthroughs and remaining controversiesAxonemal positioning and orientation in three-dimensional space for primary cilia: what is known, what is assumed, and what needs clarificationForce and the spindle: mechanical cues in mitotic spindle orientationOriented divisions, fate decisionsMolecular pathways regulating mitotic spindle orientation in animal cellsPaneth cells in intestinal homeostasis and tissue injuryModelling the spatio-temporal cell dynamics reveals novel insights on cell differentiation and proliferation in the small intestinal cryptFocal adhesions control cleavage furrow shape and spindle tilt during mitosisA two-dimensional model of the colonic crypt accounting for the role of the basement membrane and pericryptal fibroblast sheathStem cell dynamics and pretumor progression in the intestinal tractQuantification of crypt and stem cell evolution in the normal and neoplastic human colonThe APC tumor suppressor is required for epithelial cell polarization and three-dimensional morphogenesisWnt and the cancer niche: paracrine interactions with gastrointestinal cancer cells undergoing asymmetric cell divisionRole of ABL family kinases in cancer: from leukaemia to solid tumoursEzrin-mediated apical integrity is required for intestinal homeostasis.ABL1 regulates spindle orientation in adherent cells and mammalian skin.The tumor suppressor Apc controls planar cell polarities central to gut homeostasis.Tumorigenic fragments of APC cause dominant defects in directional cell migration in multiple model systemsA microRNA miR-34a-regulated bimodal switch targets Notch in colon cancer stem cells.Automated tracking of mitotic spindle pole positions shows that LGN is required for spindle rotation but not orientation maintenance.Single-molecule genomic data delineate patient-specific tumor profiles and cancer stem cell organization.Dlg1 controls planar spindle orientation in the neuroepithelium through direct interaction with LGN.A microRNA-operated switch of asymmetric-to-symmetric cancer stem cell divisions.A resource for discovering specific and universal biomarkers for distributed stem cellsRole of heterozygous APC mutation in niche succession and initiation of colorectal cancer--a computational studyStrand-seq: a unifying tool for studies of chromosome segregation.Cell adhesion in regulation of asymmetric stem cell division.Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory informationThe LKB1 tumor suppressor controls spindle orientation and localization of activated AMPK in mitotic epithelial cells.Stem cell ageing and non-random chromosome segregation.Mitotic bookmarking of genes: a novel dimension to epigenetic control.Age-dependent transition from cell-level to population-level control in murine intestinal homeostasis revealed by coalescence analysis.Drosophila male germline stem cells do not asymmetrically segregate chromosome strands.Tracking adult stem cells.
P2860
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P2860
Spindle orientation bias in gut epithelial stem cell compartments is lost in precancerous tissue.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh-hant
name
Spindle orientation bias in gu ...... s lost in precancerous tissue.
@en
Spindle orientation bias in gu ...... s lost in precancerous tissue.
@nl
type
label
Spindle orientation bias in gu ...... s lost in precancerous tissue.
@en
Spindle orientation bias in gu ...... s lost in precancerous tissue.
@nl
prefLabel
Spindle orientation bias in gu ...... s lost in precancerous tissue.
@en
Spindle orientation bias in gu ...... s lost in precancerous tissue.
@nl
P2093
P50
P1433
P1476
Spindle orientation bias in gu ...... is lost in precancerous tissue
@en
P2093
Francis A Carey
Hans Clevers
Nick Barker
Paul L Appleton
Rachel A Ridgway
P304
P356
10.1016/J.STEM.2009.12.007
P407
P577
2010-02-01T00:00:00Z