Modulating hedgehog signaling can attenuate the severity of osteoarthritis. - Wikidata - awgldk - TriplyDB

Modulating hedgehog signaling can attenuate the severity of osteoarthritis.

Modulating hedgehog signaling can attenuate the severity of osteoarthritis.

http://www.wikidata.org/entity/Q51922455

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Current research on pharmacologic and regenerative therapies for osteoarthritis Emerging regulators of the inflammatory process in osteoarthritis Osteoarthritis pathogenesis: a review of molecular mechanisms Articular Cartilage: Structural and Developmental Intricacies and Questions Endoplasmic Reticulum Stress and Unfolded Protein Response in Cartilage Pathophysiology; Contributing Factors to Apoptosis and Osteoarthritis.Integration of gene expression data with network-based analysis to identify signaling and metabolic pathways regulated during the development of osteoarthritis Prolonged application of high fluid shear to chondrocytes recapitulates gene expression profiles associated with osteoarthritis.Indian hedgehog in synovial fluid is a novel marker for early cartilage lesions in human knee joint.Signaling pathways in cartilage repair.MicroRNA-140 plays dual roles in both cartilage development and homeostasis.CCAAT/enhancer binding protein β regulates expression of Indian hedgehog during chondrocytes differentiation.Establishment of a surgically-induced model in mice to investigate the protective role of progranulin in osteoarthritis.Gene expression analyses of subchondral bone in early experimental osteoarthritis by microarray.Identification of a central role for complement in osteoarthritis.Identification of α2-macroglobulin as a master inhibitor of cartilage-degrading factors that attenuates the progression of posttraumatic osteoarthritis Hypertrophic differentiation of chondrocytes in osteoarthritis: the developmental aspect of degenerative joint disorders Decreased histone deacetylase 4 is associated with human osteoarthritis cartilage degeneration by releasing histone deacetylase 4 inhibition of runt-related transcription factor-2 and increasing osteoarthritis-related genes: a novel mechanism of hum Similar properties of chondrocytes from osteoarthritis joints and mesenchymal stem cells from healthy donors for tissue engineering of articular cartilage.TGF-β signaling and the development of osteoarthritis A role for hedgehog signaling in the differentiation of the insertion site of the patellar tendon in the mouse.Sonic hedgehog improves redifferentiation of dedifferentiated chondrocytes for articular cartilage repair.Expression of hedgehog signal pathway in articular cartilage is associated with the severity of cartilage damage in rats with adjuvant-induced arthritis.Genetic evidence of the regulatory role of parathyroid hormone-related protein in articular chondrocyte maintenance in an experimental mouse model.Teriparatide as a chondroregenerative therapy for injury-induced osteoarthritis.Proteases involved in cartilage matrix degradation in osteoarthritis.Indian Hedgehog signaling pathway members are associated with magnetic resonance imaging manifestations and pathological scores in lumbar facet joint osteoarthritis Emerging targets in osteoarthritis therapy.α-Catenin inhibits β-catenin-T-cell factor/lymphoid enhancing factor transcriptional activity and collagen type II expression in articular chondrocytes through formation of Gli3R.α-catenin.β-catenin ternary complex.MicroRNA-602 and microRNA-608 regulate sonic hedgehog expression via target sites in the coding region in human chondrocytes Activation of Indian hedgehog promotes chondrocyte hypertrophy and upregulation of MMP-13 in human osteoarthritic cartilage Epigenetic mechanisms underlying the aberrant catabolic and anabolic activities of osteoarthritic chondrocytes.Interruption of glycosphingolipid synthesis enhances osteoarthritis development in mice.Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis Chondrogenesis, chondrocyte differentiation, and articular cartilage metabolism in health and osteoarthritis.Do mouse models reflect the diversity of osteoarthritis in humans?Regulation of Cholesterol Homeostasis by Hedgehog Signaling in Osteoarthritic Cartilage.Hedgehog signalling does not stimulate cartilage catabolism and is inhibited by Interleukin-1β New findings in osteoarthritis pathogenesis: therapeutic implications.Response of knee fibrocartilage to joint destabilization.The Role of miRNAs in Cartilage Homeostasis.

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Modulating hedgehog signaling can attenuate the severity of osteoarthritis.

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Modulating hedgehog signaling can attenuate the severity of osteoarthritis.

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Modulating hedgehog signaling can attenuate the severity of osteoarthritis.

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Modulating hedgehog signaling can attenuate the severity of osteoarthritis.

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Modulating hedgehog signaling can attenuate the severity of osteoarthritis.

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Modulating hedgehog signaling can attenuate the severity of osteoarthritis.

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Modulating hedgehog signaling can attenuate the severity of osteoarthritis.

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Benjamin A Alman

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