In silico identification of the key components and steps in IFN-gamma induced JAK-STAT signaling pathway.
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Two independent positive feedbacks and bistability in the Bcl-2 apoptotic switchSobol Sensitivity Analysis: A Tool to Guide the Development and Evaluation of Systems Pharmacology ModelsSustained oscillations of NF-kappaB produce distinct genome scanning and gene expression profilesParameter trajectory analysis to identify treatment effects of pharmacological interventionsSensitivity analysis of intracellular signaling pathway kinetics predicts targets for stem cell fate control.SBML-SAT: a systems biology markup language (SBML) based sensitivity analysis tool.Comparative analysis of the JAK/STAT signaling through erythropoietin receptor and thrombopoietin receptor using a systems approach.Combining theoretical analysis and experimental data generation reveals IRF9 as a crucial factor for accelerating interferon α-induced early antiviral signalling.A computational and experimental study of the regulatory mechanisms of the complement systemUnderstanding dynamics using sensitivity analysis: caveat and solutionMuscle-type specific autophosphorylation of CaMKII isoforms after paced contractions.Tav4SB: integrating tools for analysis of kinetic models of biological systemsDevelopment of a sampling-based global sensitivity analysis workflow for multiscale computational cancer modelsOscillations in MAPK cascade triggered by two distinct designs of coupled positive and negative feedback loops.Different designs of kinase-phosphatase interactions and phosphatase sequestration shapes the robustness and signal flow in the MAPK cascade.An agent-based model of cellular dynamics and circadian variability in human endotoxemia.Elucidating the crosstalk mechanism between IFN-gamma and IL-6 via mathematical modelling.Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range.Quantitative Modeling of the Alternative Pathway of the Complement SystemReduced-order modelling of biochemical networks: application to the GTPase-cycle signalling moduleTime to Decide? Dynamical Analysis Predicts Partial Tip/Stalk Patterning States Arise during Angiogenesis.Cytokine response is determined by duration of receptor and signal transducers and activators of transcription 3 (STAT3) activationComputational models of the JAK1/2-STAT1 signalingMagnitude and control of mitochondrial sensitivity to ADP.Mathematical modeling as a tool for planning anticancer therapy.Cross-scale sensitivity analysis of a non-small cell lung cancer model: linking molecular signaling properties to cellular behaviorSystematic calibration of a cell signaling network model.Developing an in silico model of the modulation of base excision repair using methoxyamine for more targeted cancer therapeutics.A multiscale model of interleukin-6-mediated immune regulation in Crohn's disease and its application in drug discovery and development.Propagation of kinetic uncertainties through a canonical topology of the TLR4 signaling network in different regions of biochemical reaction space.Complex systems biology approach to understanding coordination of JAK-STAT signaling.Identification of Critical Molecular Components in a Multiscale Cancer Model Based on the Integration of Monte Carlo, Resampling, and ANOVA.Modular metabolic control analysis of large responses in branched systems--application to aspartate metabolism.Reducing experimental variability in variance-based sensitivity analysis of biochemical reaction systems.Characterization of the adaptive response and growth upon hyperosmotic shock in Saccharomyces cerevisiae.Mathematical model of PAR1-mediated activation of human platelets.Cellular signaling is potentially regulated by cell density in receptor trafficking networks.Perspectives on mathematical modeling for receptor-mediated processes.
P2860
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P2860
In silico identification of the key components and steps in IFN-gamma induced JAK-STAT signaling pathway.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
In silico identification of th ...... ed JAK-STAT signaling pathway.
@en
In silico identification of th ...... ed JAK-STAT signaling pathway.
@nl
type
label
In silico identification of th ...... ed JAK-STAT signaling pathway.
@en
In silico identification of th ...... ed JAK-STAT signaling pathway.
@nl
prefLabel
In silico identification of th ...... ed JAK-STAT signaling pathway.
@en
In silico identification of th ...... ed JAK-STAT signaling pathway.
@nl
P2093
P2860
P1433
P1476
In silico identification of th ...... ed JAK-STAT signaling pathway.
@en
P2093
Jiashun Zheng
Myong-Hee Sung
Xuefeng Xia
Zhirong Sun
P2860
P304
P356
10.1016/J.FEBSLET.2005.01.009
P407
P577
2005-02-01T00:00:00Z