Cutting edge: T cell development requires the combined activities of the p110gamma and p110delta catalytic isoforms of phosphatidylinositol 3-kinase.
about
Tripartite motif containing protein 27 negatively regulates CD4 T cells by ubiquitinating and inhibiting the class II PI3K-C2βTherapeutic targeting of replicative immortalityp110γ/δ Double-Deficiency Induces Eosinophilia and IgE Production but Protects from OVA-Induced Airway InflammationSignaling by the phosphoinositide 3-kinase family in immune cellsPIP3 pathway in regulatory T cells and autoimmunityTumor-shed PGE(2) impairs IL2Rgammac-signaling to inhibit CD4 T cell survival: regulation by theaflavins.Targeting phosphoinositide-3-kinase-delta with theophylline reverses corticosteroid insensitivity in chronic obstructive pulmonary disease.Tenuous paths in unexplored territory: From T cell receptor signaling to effector gene expression during thymocyte selection.TCR-induced Akt serine 473 phosphorylation is regulated by protein kinase C-alphaLipid signaling in T-cell development and functionRole of PI3Kdelta and PI3Kgamma in inflammatory arthritis and tissue localization of neutrophils.PI3Kδ is essential for tumor clearance mediated by cytotoxic T lymphocytes.PI3Kγ drives priming and survival of autoreactive CD4(+) T cells during experimental autoimmune encephalomyelitis.Functional redundancy of class I phosphoinositide 3-kinase (PI3K) isoforms in signaling growth factor-mediated human neutrophil survivalSuppression of leukemia development caused by PTEN loss.Antigen receptor signalling: a distinctive role for the p110delta isoform of PI3K.Emergence of the PI3-kinase pathway as a central modulator of normal and aberrant B cell differentiationCritical role for phosphoinositide 3-kinase gamma in parasite invasion and disease progression of cutaneous leishmaniasis.T-cell function is partially maintained in the absence of class IA phosphoinositide 3-kinase signaling.PI3Ks in lymphocyte signaling and developmentPhosphoinositide 3-kinase gamma participates in T cell receptor-induced T cell activation.The Therapeutic Potential for PI3K Inhibitors in Autoimmune Rheumatic DiseasesRegulation of CD38 expression in human airway smooth muscle cells: role of class I phosphatidylinositol 3 kinasesPI3K signalling in B- and T-lymphocytes: new developments and therapeutic advancesPhosphatidylinositol 3-Kinase p110δ Isoform Regulates CD8+ T Cell Responses during Acute Viral and Intracellular Bacterial InfectionsThe p110gamma isoform of phosphatidylinositol 3-kinase regulates migration of effector CD4 T lymphocytes into peripheral inflammatory sites.Phosphoinositide 3-kinase signalling in lung disease: leucocytes and beyond.Role of phosphoinositide 3-kinase signaling in autoimmunity.Lymphocyte cell motility: the twisting, turning tale of phosphoinositide 3-kinase.Phosphoinositide lipid phosphatases: natural regulators of phosphoinositide 3-kinase signaling in T lymphocytes.Critical roles of the PI3K/Akt signaling pathway in T cell developmentThe microRNA miR-181 is a critical cellular metabolic rheostat essential for NKT cell ontogenesis and lymphocyte development and homeostasis.Regulation of T-cell migration and effector functions: insights from in vivo imaging studies.T-cell-targeted signaling inhibitors.p110gamma and p110delta isoforms of phosphoinositide 3-kinase differentially regulate natural killer cell migration in health and diseaseRegulation of T-cell responses by PTENThe class II phosphatidylinositol 3 kinase C2beta is required for the activation of the K+ channel KCa3.1 and CD4 T-cells.Peripheral T cells in the thymus: have they just lost their way or do they do something?New insights into the regulation and function of serine/threonine kinases in T lymphocytes.Fine tuning the immune response with PI3K.
P2860
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P2860
Cutting edge: T cell development requires the combined activities of the p110gamma and p110delta catalytic isoforms of phosphatidylinositol 3-kinase.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
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2005年學術文章
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name
Cutting edge: T cell developme ...... phosphatidylinositol 3-kinase.
@en
Cutting edge: T cell developme ...... phosphatidylinositol 3-kinase.
@nl
type
label
Cutting edge: T cell developme ...... phosphatidylinositol 3-kinase.
@en
Cutting edge: T cell developme ...... phosphatidylinositol 3-kinase.
@nl
prefLabel
Cutting edge: T cell developme ...... phosphatidylinositol 3-kinase.
@en
Cutting edge: T cell developme ...... phosphatidylinositol 3-kinase.
@nl
P2093
P1476
Cutting edge: T cell developme ...... phosphatidylinositol 3-kinase.
@en
P2093
Elena Vigorito
Louise M C Webb
Martin Turner
P304
P356
10.4049/JIMMUNOL.175.5.2783
P407
P577
2005-09-01T00:00:00Z